Tick–pathogen interactions: the metabolic perspective

A Cabezas-Cruz, P Espinosa, P Alberdi… - Trends in …, 2019 - cell.com
The first tick genome published in 2016 provided an invaluable tool for studying the
molecular basis of tick–pathogen interactions. Metabolism is a key element in host …

Integrated metabolomics, transcriptomics and proteomics identifies metabolic pathways affected by anaplasma phagocytophilum infection in tick cells*[S]

M Villar, N Ayllón, P Alberdi, A Moreno… - Molecular & Cellular …, 2015 - ASBMB
Anaplasma phagocytophilum is an emerging zoonotic pathogen that causes human
granulocytic anaplasmosis. These intracellular bacteria establish infection by affecting cell …

Tick-pathogen interactions and vector competence: identification of molecular drivers for tick-borne diseases

J De la Fuente, S Antunes, S Bonnet… - Frontiers in cellular …, 2017 - frontiersin.org
Ticks and the pathogens they transmit constitute a growing burden for human and animal
health worldwide. Vector competence is a component of vectorial capacity and depends on …

Modeling Modulation of the Tick Regulome in Response to Anaplasma phagocytophilum for the Identification of New Control Targets

S Artigas-Jerónimo, A Estrada-Peña… - Frontiers in …, 2019 - frontiersin.org
Ticks act as vectors of pathogens affecting human and animal health worldwide, and recent
research has focused on the characterization of tick-pathogen interactions using omics …

A systems biology approach to better understand human tick-borne diseases

W Lee, AD Barbosa, PJ Irwin, A Currie… - Trends in …, 2023 - cell.com
Tick-borne diseases (TBDs) are a growing global health concern. Despite extensive studies,
ill-defined tick-associated pathologies remain with unknown aetiologies. Human …

Sialomes and mialomes: a systems-biology view of tick tissues and tick–host interactions

J Chmelař, J Kotál, S Karim, P Kopacek… - Trends in …, 2016 - cell.com
Tick saliva facilitates tick feeding and infection of the host. Gene expression analysis of tick
salivary glands and other tissues involved in host–pathogen interactions has revealed a …

Interaction of the tick immune system with transmitted pathogens

O Hajdušek, R Šíma, N Ayllón, M Jalovecká… - Frontiers in cellular …, 2013 - frontiersin.org
Ticks are hematophagous arachnids transmitting a wide variety of pathogens including
viruses, bacteria, and protozoans to their vertebrate hosts. The tick vector competence has to …

Evolutionary insights into the tick hologenome

S Díaz-Sánchez, A Estrada-Peña, A Cabezas-Cruz… - Trends in …, 2019 - cell.com
Recently, our knowledge of the composition and complexity of tick microbial communities
has increased and supports microbial impact on tick biology. Results support a phylogenetic …

The case for oxidative stress molecule involvement in the tick-pathogen interactions-an omics approach

EP Hernandez, MR Talactac, K Fujisaki… - Developmental & …, 2019 - Elsevier
The blood-feeding behavior of ticks has resulted in them becoming one of the most
important vectors of disease-causing pathogens. Ticks possess a well-developed innate …

[HTML][HTML] Current debates and advances in tick microbiome research

A Wu-Chuang, A Hodžić, L Mateos-Hernández… - Current research in …, 2021 - Elsevier
The main importance of ticks resides in their ability to harbor pathogens that can be
transmitted to terrestrial vertebrates including humans. Recently, studies have focused on …