Downregulation of the major autolysin in Streptococcus pneumoniae leads to penicillin
tolerance, a feature that is characterized by the ability to survive but not grow in the presence …

The psaBCA locus of Streptococcus pneumoniae encodes a putative ABC Mn2+‐permease
complex. Downstream of the operon is psaD, which may be co‐transcribed and encodes a …

The adcCBA putative operon of Streptococcus pneumoniae, an important human pathogen,
was identified in a search for transformation‐deficient mutants. It was found to exhibit …

PsaA of Streptococcus pneumoniae, originally believed to be an adhesin, is the lipoprotein
component of an Mn2+ transporter. Mutations in psaA cause deficiencies in growth …

Recently, it was shown that a significant number of erythromycin-resistant Streptococcus
pneumoniae and Streptococcus pyogenes strains contain a determinant that mediates …

We have sequenced the penicillin-binding domains of the complete repertoire of penicillin-
binding proteins and MurM from 22 clinical isolates of Streptococcus pneumoniae that span …

Differential fluorescence induction technology was used to identify promoters of
Streptococcus pneumoniae genes that are expressed during lung infection of the mouse …

Target alteration underlies resistance to β-lactam antibiotics in both Staphylococcus species
and Streptococcus pneumoniae. The penicillin-binding protein (PBP) targets in penicillin …

The recent emergence of pneumococcal isolates exhibiting an unusual resistance
phenotype of higher amoxicillin MICs in relation to the penicillin MICs prompted an analysis …

Piperacillin resistance in Streptococcus pneumoniae was mediated by mutations in a novel
gene, cpoA, that also confer transformation deficiency and a decrease in penicillin-binding …