SB Elmariah, JS Smith, JF Merola - American journal of clinical …, 2022 - Springer
Janus kinase (JAK) inhibitors are immunomodulatory agents with broad potential for use within dermatology. However, the US Food and Drug Administration has recently placed …
P Ciechanowicz, A Rakowska, M Sikora… - Journal of …, 2019 - Taylor & Francis
The Janus kinase (JAK) and signal transducer and activator of transcription (STAT) pathway is a ubiquitous intracellular signaling network. Selective JAK-inhibitors have anti …
A Cinats, E Heck, L Robertson - Skin therapy letter, 2018 - europepmc.org
The class of medications known as Janus kinase inhibitors block cytokine-mediated signaling via the Janus kinase-signal transducer and activator of transcription (JAK-STAT) …
R Shreberk-Hassidim, Y Ramot, A Zlotogorski - Journal of the American …, 2017 - Elsevier
Background Janus kinase (JAK) inhibitors are emerging as a promising new treatment modality for many inflammatory conditions. Objective Our aim was to systematically review …
Importance Janus kinase (JAK) inhibitors are an effective treatment option for patients with certain skin-related conditions, such as atopic dermatitis, alopecia areata, and vitiligo, but …
Background Janus kinase (JAK) inhibitors have attracted attention for their role in treating inflammatory disorders. This new class of biologics has the potential to significantly affect the …
S Mori, F Ogata, R Tsunoda - Clinical Rheumatology, 2021 - Springer
Janus kinase (JAK) inhibitors have been developed as disease-modifying antirheumatic drugs. Despite the positive therapeutic impacts of JAK inhibitors, concerns have been raised …
Janus kinase family (JAKs) has recently attracted the attention of many researchers, and several JAK inhibitor drugs have been developed targeting different members of the JAK …
R Westhovens - Rheumatology, 2019 - academic.oup.com
Janus kinase inhibition is promising in the treatment of RA, with already two oral drugs marketed. New compounds are under investigation that are more selective for Janus kinase …