[HTML][HTML] In vitro activity of therapeutic antibodies against SARS-CoV-2 Omicron BA. 1, BA. 2 and BA. 5

F Touret, C Baronti, B Pastorino, PMS Villarroel… - Scientific Reports, 2022 - nature.com
The replacement of the Omicron BA. 1 variant of SARS-CoV-2 by the BA. 2 and the rapid
growth of the BA. 5 sub lineage, which have both different sets of mutations in the spike …

[HTML][HTML] In vitro evaluation of therapeutic antibodies against a SARS-CoV-2 Omicron B. 1.1. 529 isolate

F Touret, C Baronti, HS Bouzidi, X de Lamballerie - Scientific Reports, 2022 - nature.com
The emergence and rapid spread of the Omicron variant of SARS-CoV-2, which has more
than 30 substitutions in the spike glycoprotein, compromises the efficacy of currently …

Sensitivity of novel SARS-CoV-2 Omicron subvariants, BA. 2.11, BA. 2.12. 1, BA. 4 and BA. 5 to therapeutic monoclonal antibodies

D Yamasoba, Y Kosugi, I Kimura, S Fujita, K Uriu, J Ito… - BioRxiv, 2022 - biorxiv.org
Abstract As of May 2022, Omicron BA. 2 variant is the most dominant variant in the world.
Thereafter, Omicron subvariants have emerged and some of them began outcompeting BA …

[HTML][HTML] Resistance of SARS-CoV-2 Omicron BA. 1 and BA. 2 variants to vaccine-elicited sera and therapeutic monoclonal antibodies

H Zhou, BM Dcosta, NR Landau, T Tada - Viruses, 2022 - mdpi.com
The recent emergence of the Omicron BA. 1 and BA. 2 variants with heavily mutated spike
proteins has posed a challenge to the effectiveness of current vaccines and to monoclonal …

[HTML][HTML] An infectious SARS-CoV-2 B. 1.1. 529 Omicron virus escapes neutralization by therapeutic monoclonal antibodies

LA VanBlargan, JM Errico, PJ Halfmann, SJ Zost… - Nature medicine, 2022 - nature.com
The emergence of the highly transmissible B. 1.1. 529 Omicron variant of severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) is concerning for antibody …

Susceptibility of SARS-CoV-2 Omicron variants to therapeutic monoclonal antibodies: systematic review and meta-analysis

K Tao, PL Tzou, SL Kosakovsky Pond… - Microbiology …, 2022 - Am Soc Microbiol
ABSTRACT SARS-CoV-2 Omicron variants contain many mutations in its spike receptor-
binding domain, the target of all authorized monoclonal antibodies (MAbs). Determining the …

[HTML][HTML] Enhanced neutralization escape to therapeutic monoclonal antibodies by SARS-CoV-2 omicron sub-lineages

F Touret, E Giraud, J Bourret, F Donati, J Tran-Rajau… - Iscience, 2023 - cell.com
The landscape of SARS-CoV-2 variants dramatically diversified with the simultaneous
appearance of multiple subvariants originating from BA. 2, BA. 4, and BA. 5 Omicron sub …

Neutralization of SARS-CoV-2 Omicron BA. 2 by therapeutic monoclonal antibodies

H Zhou, T Tada, BM Dcosta, NR Landau - Biorxiv, 2022 - ncbi.nlm.nih.gov
Monoclonal antibody therapy for the treatment of SARS-CoV-2 infection has been highly
successful in decreasing disease severity; however, the recent emergence of the heavily …

[HTML][HTML] Efficacy of licensed monoclonal antibodies and antiviral agents against the SARS-CoV-2 omicron sublineages BA. 1 and BA. 2

L Fiaschi, F Dragoni, E Schiaroli, A Bergna, B Rossetti… - Viruses, 2022 - mdpi.com
Newly emerging SARS-CoV-2 variants may escape monoclonal antibodies (mAbs) and
antiviral drugs. By using live virus assays, we assessed the ex vivo inhibition of the B. 1 wild …

[HTML][HTML] Antigenic characterization of the SARS-CoV-2 Omicron subvariant BA. 2.75

Q Wang, S Iketani, Z Li, Y Guo, AY Yeh, M Liu, J Yu… - Cell host & …, 2022 - cell.com
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron subvariant
BA. 2.75 emerged recently and appears to be spreading. It has nine mutations in spike …