Adequate skeletal muscle plasticity is an essential element for our well-being, and
compromised muscle function can drastically affect quality of life, morbidity, and mortality …

Atrophy occurs in specific muscles with inactivity (for example, during plaster cast
immobilization) or denervation (for example, in patients with spinal cord injuries). Muscle …

Muscle wasting and weakness are common in many disease states and conditions including
aging, cancer cachexia, sepsis, denervation, disuse, inactivity, burns, HIV-acquired …

Loss of muscle mass can be the consequence of pathological changes, as observed in
muscular dystrophies; or it can be secondary to cachexia-inducing diseases that cause …

Over the last two decades, new insights into the etiology of skeletal muscle wasting/atrophy
under diverse clinical settings including denervation, AIDS, cancer, diabetes, and chronic …

Skeletal muscle is a crucial tissue for movement, gestural assistance, metabolic
homeostasis, and thermogenesis. It makes up approximately 40% of the total body weight …

Skeletal muscle is a highly specialized, postmitotic tissue that must withstand chronic
mechanical and physiological stress throughout life to maintain proper contractile function …

Muscle wasting is associated with several human diseases such as muscle dystrophies or
cancer cachexia. However, currently there are no effective treatments for this condition, and …

The recent advances in our understanding of the biology of muscle, and how anabolic and
catabolic stimuli interact to control muscle mass and function, have led to new interest in …

Skeletal muscle wasting occurs in both chronic and acute diseases. Increasing evidence
has shown this debilitating process is associated with short-and long-term outcomes in …