Ursodeoxycholic acid (UDCA) makes up a small portion of the naturally occurring bile acid
pool in humans, and the drug is effective in several diseases. The mechanism of action …

Ursodeoxycholic acid is a hydrophilic bile acid that under normal circumstances represents
a small fraction of the bile acid pool in humans. It is effective in dissolving cholesterol …

Ursodeoxycholic acid (UDCA) is widely used for the treatment of a variety of chronic
cholestatic liver diseases. The possible mechanisms of action include stimulation of …

Ursodeoxycholic acid (UDCA) has beneficial effects on symptoms, liver biochemistry and,
possibly, liver histology in primary biliary cirrhosis and other cholestatic liver diseases …

Abstract Ursodeoxycholic acid (UDCA), the 7β-epimer of chenodeoxycholic acid, has
multiple hepatoprotective activities. UDCA modifies the bile acid pool, decreasing levels of …

Ursodeoxycholic acid (UDCA), previously used for cholesterol gallstone dissolution, is
currently considered the first choice therapy for many forms of cholestatic syndromes. Many …

The hydrophilic bile acid ursodeoxycholic acid has recently been shown to reduce
biochemical markers of both cholestasis and hepatocellular damage in patients with chronic …

Ursodeoxycholic acid is currently the only established drug for the treatment of chronic
cholestatic liver diseases. It has cytoprotective, anti‐apoptotic, membrane stabilizing, anti …

Ursodeoxycholic acid (UDCA) is an established and accepted treatment of biliary diseases
such as gallstones and primary biliary cirrhosis. Mechanisms of action of UDCA are not so …

Ursodeoxycholic acid is a dihydroxy bile acid with a rapidly expanding spectrum of usage in
acute and chronic liver diseases. The various mechanisms of action of this hydrophilic bile …