The effects of metoprolol treatment in patients surviving acute myocardial infarction have
been investigated in a double-blind randomized study. The patients were stratified …

The effect of metoprolol on mortality and morbidity after 15 days, was compared with that of
placebo in a double-blind randomised international trial (the MIAMI trial) in patients with …

In the Göteborg Metoprolol Trial, 1395 patients with suspected acute myocardial infarction
were, on admission, randomly allocated to double-blind treatment, 697 to placebo and 698 …

In a randomized double-blind postinfarction study 301 patients were treated with either
metoprolol 100 mg bid (n= 154) or placebo (n= 147) for three years. After the three-year …

The effect of metoprolol on mortality was compared with that of placebo in a double-blind
randomised trial in patients with definite or suspected acute myocardial infarction. Treatment …

Several postinfarction trials have evaluated the effect of secondary prophylaxis with different
beta-blockers. Although so called meta-analysis of the results from all the trials have shown …

During a double-blind trial in which patients with suspected myocardial infarction received
metoprolol or placebo, we analyzed the occurrence of ventricular tachyarrhythmias …

Abstract The Lopressor Intervention Trial (LIT) was a double-blind, randomized, placebo-
controlled, multicentre study designed to evaluate the effect of oral metoprolol on overall …

During the 3-month blind treatment period there were 40 deaths in the metoprolol group
compared with 62 deaths in the placebo group (p= 0.024). During the first year (after 3 …

After 15 days there were 142 deaths in the placebo group (4.9%) and 123 deaths in the
metoprolol group (4.3%), a difference of 13%(p= 0.29). The 95% confidence limits for the …