Fig. 1.—Conventional and diffusion-tensor MR images from newborn boy of 26 weeks'
estimated gestational age. Single arrows= occipital horns of lateral ventricles. A, Axial T1 …

Diffusional anisotropy of human brain was investigated clinically in six adult volunteers,
eight premature neonates, and three infants aged 5-10 months. Diffusion-weighted magnetic …

PURPOSE To analyze diffusional anisotropy in frontal and occipital white matter of human
brain quantitatively as a function of age by using diffusion-weighted MR imaging. METHODS …

In vivo magnetic resonance (MR) images of the brain in neonates and infants up to 24
months of age were retrospectively studied to evaluate normal maturation patterns in the …

Purpose To determine the change over time of the apparent diffusion coefficient (ADC) and
relative anisotropy of cerebral water in a cohort of premature newborns serially studied near …

BACKGROUND AND PURPOSE: Conventional MR imaging findings of human brain
development are thought to result from decreasing water content, increasing …

The pattern of normal white-matter maturation as demonstrated with high-field-strength
magnetic resonance (MR) imaging was investigated. Eighty-two neurologically normal …

Purpose: This study was designed to compare the sensitivity of T1-and diffusion-weighted
images for the assessment of brain maturation in human brains. Methods: T1-and diffusion …

PURPOSE: To establish quantitative standards for the directionally averaged water apparent
diffusion coefficient (D) and quantitative diffusion anisotropy (A sigma) of normal brains in …

19 macromolecules, such as myelin [1, 2]. In particular, T1 and T2 relaxation times become
shorter as myelination progresses, allowing visualization of white matter maturation in …