Post-translational modifications of proteins control many biological processes, and
examining their diversity is critical for understanding mechanisms of cell regulation. Mass …

Most biological processes are regulated by post-translational modifications of proteins, and
conditions that disrupt the regulation of such events can lead to disease. In the past decade …

Post-translational modifications generate tremendous diversity, complexity and
heterogeneity of gene products, and their determination is one of the main challenges in …

Post-translational modifications modulate the activity of most eukaryote proteins. Analysis of
these modifications presents formidable challenges but their determination generates …

Major recent advances in hardware performance, sample-handling procedures and software
algorithms now allow reliable and sensitive mass spectrometric identification of proteins …

Cellular function can be controlled through the gene expression program, but often protein
post-translational modifications (PTMs) provide a more precise and elegant mechanism. Key …

Post-translational modifications (PTMs) create vast structural and functional diversity of
proteins, ultimately modulating protein function and degradation, influencing cellular …

Is Proteomics the New Genomics?: Cell Skip to Main Content Advertisement Cell This
journal offers authors two options (open access or subscription) to publish research This …

Protein activity and turnover is tightly and dynamically regulated in living cells. Whereas the
three-dimensional protein structure is predominantly determined by the amino acid …

Posttranslational modifications (PTMs) of proteins perform crucial roles in regulating the
biology of the cell. PTMs are enzymatic, covalent chemical modifications of proteins that …