Age-severity matched cytokine profiling reveals specific signatures in Covid-19 patients

R Angioni, R Sanchez-Rodriguez, F Munari… - Cell death & …, 2020 - nature.com
A global effort is currently undertaken to restrain the COVID-19 pandemic. Host immunity
has come out as a determinant for COVID-19 clinical outcomes, and several studies …

Cytokine signature and COVID-19 prediction models in the two waves of pandemics

S Cabaro, V D'Esposito, T Di Matola, S Sale… - Scientific Reports, 2021 - nature.com
In Europe, multiple waves of infections with SARS-CoV-2 (COVID-19) have been observed.
Here, we have investigated whether common patterns of cytokines could be detected in …

Serial measurement of cytokines strongly predict COVID-19 outcome

HS Ozger, R Karakus, EN Kuscu, UE Bagriacik… - PloS one, 2021 - journals.plos.org
Purpose Cytokines are major mediators of COVID-19 pathogenesis and several of them are
already being regarded as predictive markers for the clinical course and outcome of COVID …

Multi-omic longitudinal study reveals immune correlates of clinical course among hospitalized COVID-19 patients

J Diray-Arce, S Fourati, ND Jayavelu, R Patel… - Cell Reports …, 2023 - cell.com
The IMPACC cohort, composed of> 1,000 hospitalized COVID-19 participants, contains five
illness trajectory groups (TGs) during acute infection (first 28 days), ranging from milder (TG1 …

The COVID-19 immune landscape is dynamically and reversibly correlated with disease severity

H Bolouri, C Speake, D Skibinski… - The Journal of …, 2021 - Am Soc Clin Investig
BACKGROUND Despite a rapidly growing body of literature on coronavirus disease 2019
(COVID-19), our understanding of the immune correlates of disease severity, course, and …

Longitudinal cytokine profile in patients with mild to critical COVID-19

L Ling, Z Chen, G Lui, CK Wong, WT Wong… - Frontiers in …, 2021 - frontiersin.org
The cytokine release syndrome has been proposed as the driver of inflammation in
coronavirus disease 2019 (COVID-19). However, studies on longitudinal cytokine profiles in …

A deep look into COVID-19 severity through dynamic changes in blood cytokine levels

DA Kleymenov, EN Bykonia, LI Popova… - Frontiers in …, 2021 - frontiersin.org
An excessive inflammatory response to SARS-CoV-2 is thought to be a major cause of
disease severity and mortality in patients with COVID-19. Longitudinal analysis of cytokine …

Immune characteristics of severe and critical COVID-19 patients

L Yang, J Gou, J Gao, L Huang, Z Zhu, S Ji… - Signal transduction and …, 2020 - nature.com
Recently, the novel coronavirus disease (COVID-19) has broken out worldwide, 1 with rapid
increase of infected patients. COVID-19 dominantly leads to pneumonia. 2 Among these …

Temporal profiling of plasma cytokines, chemokines and growth factors from mild, severe and fatal COVID-19 patients

ZS Xu, T Shu, L Kang, D Wu, X Zhou, BW Liao… - Signal transduction and …, 2020 - nature.com
In December 2019, a novel coronavirus that is related to severe acute respiratory syndrome
coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV) in …

[HTML][HTML] An immune-based biomarker signature is associated with mortality in COVID-19 patients

MS Abers, OM Delmonte, EE Ricotta, J Fintzi, DL Fink… - JCI insight, 2021 - ncbi.nlm.nih.gov
Immune and inflammatory responses to severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) contribute to disease severity of coronavirus disease 2019 (COVID-19) …