NPR-A: a therapeutic target in inflammation and cancer

J Zhang, M Li, Y Yang, Y Yan, J Li… - Critical Reviews™ in …, 2015 - dl.begellhouse.com
Natriuretic peptide receptor A (NPR-A) is the receptor for atrial natriuretic peptide (ANP) and
brain natriuretic peptide (BNP). NPR-A plays critical physiological and pathophysiological …

[HTML][HTML] Impact of NPR-A expression in gastric cancer cells

J Zhang, J Qu, Y Yang, M Li, M Zhang… - … Journal of Clinical …, 2014 - ncbi.nlm.nih.gov
Background: The receptors for the cardiac hormone atrial natriuretic peptide (ANP),
natriuretic peptide receptor A (NPR-A), have been reported to be expressed in lung cancer …

Natriuretic peptide receptor A signaling regulates stem cell recruitment and angiogenesis: a model to study linkage between inflammation and tumorigenesis

J Mallela, S Ravi, F Jean Louis, B Mulaney… - Stem …, 2013 - academic.oup.com
Natriuretic peptide receptor A (NPRA), the signaling receptor for the cardiac hormone, atrial
natriuretic peptide (ANP), is expressed abundantly in inflamed/injured tissues and tumors …

ANP-NPRA Signaling Pathway− A Potential Therapeutic Target for the Treatment of Malignancy

Z Zhao, J Zhang, M Li, Y Yang, K Sun… - Critical Reviews™ in …, 2013 - dl.begellhouse.com
It was well established that the atrial natriuretic peptide (ANP)/natriuretic peptide receptor-A
(NPRA) signaling pathway controls natriuretic, diuretic, vasorelaxant, and anti-proliferative …

Natriuretic peptide receptor A as a novel target for cancer

J Zhang, Z Zhao, J Wang - World Journal of Surgical Oncology, 2014 - Springer
The receptor for the cardiac hormone atrial natriuretic peptide (ANP), natriuretic peptide
receptor A (NPR-A), has been reported to be expressed in lung cancer, prostate cancer and …

Natriuretic peptide receptor a as a novel anticancer target

X Kong, X Wang, W Xu, S Behera, G Hellermann… - Cancer research, 2008 - AACR
The receptor for atrial natriuretic peptide (ANP), natriuretic peptide receptor A (NPRA), is
expressed in cancer cells, and natriuretic peptides have been implicated in cancers …

Pleiotropic roles of atrial natriuretic peptide in anti-inflammation and anti-cancer activity

H Fu, J Zhang, Q Cai, Y He, D Yang - Cancers, 2022 - mdpi.com
Simple Summary The relationship between inflammation and carcinogenesis, as well as the
response to anti-tumor therapy, is intimate. Atrial natriuretic peptides (ANPs) play a pivotal …

NPR-C: a component of the natriuretic peptide family with implications in human diseases

S Rubattu, S Sciarretta, A Morriello, C Calvieri… - Journal of molecular …, 2010 - Springer
The natriuretic peptide (NP) family includes atrial natriuretic peptide (ANP), B-type natriuretic
peptide, C-type natriuretic peptide and their receptors NPR-A, NPR-B and NPR-C. The …

Endothelial natriuretic peptide receptor 1 play crucial role for acute and chronic blood pressure regulation by atrial natriuretic peptide

T Tokudome, K Otani, Y Mao, LJ Jensen, Y Arai… - …, 2022 - Am Heart Assoc
Background: ANP (atrial natriuretic peptide), acting through NPR1 (natriuretic peptide
receptor 1), provokes hypotension. Such hypotension is thought to be due to ANP inducing …

[HTML][HTML] Natriuretic peptide receptor a promotes breast cancer development by upregulating MMP9

J Qu, X Zhao, X Liu, Y Sun, J Wang, L Liu… - American journal of …, 2019 - ncbi.nlm.nih.gov
Natriuretic peptide receptor A (NPRA), one of the natriuretic peptide receptors, plays
important roles in circulatory system. Recently some studies showed that NPRA was …