Epigenetics of aging and disease: a brief overview

C Pagiatakis, E Musolino, R Gornati… - Aging clinical and …, 2021 - Springer
Aging is an important risk factor for several human diseases such as cancer, cardiovascular
disease and neurodegenerative disorders, resulting from a combination of genetic and …

The role of epigenetics in aging and age-related diseases

V Calvanese, E Lara, A Kahn, MF Fraga - Ageing research reviews, 2009 - Elsevier
The role of epigenetics in aging and age-related diseases is a key issue in molecular
physiology and medicine because certain epigenetic factors are thought to mediate, at least …

Epigenetic mechanisms of aging and aging-associated diseases

A la Torre, F Lo Vecchio, A Greco - Cells, 2023 - mdpi.com
Aging is an inevitable outcome of life, characterized by a progressive decline in tissue and
organ function. At a molecular level, it is marked by the gradual alterations of biomolecules …

Epigenetic factors in aging and longevity

S Gravina, J Vijg - Pflügers Archiv-European Journal of Physiology, 2010 - Springer
Epigenetics refers to phenotypic changes caused by mechanisms that are unrelated to
changes in the underlying DNA sequence, most notably chromatin remodeling driven by …

[HTML][HTML] Epigenetic regulation of aging

S Rodríguez-Rodero… - Discovery …, 2010 - discoverymedicine.com
Aging is one of the most challenging and unresolved problems in biology owing to its highly
complex nature. Public interest in aging has increased not only because all of us can expect …

Epigenetics of aging and aging-associated diseases

D Saul, RL Kosinsky - International journal of molecular sciences, 2021 - mdpi.com
Aging represents the multifactorial decline in physiological function of every living organism.
Over the past decades, several hallmarks of aging have been defined, including epigenetic …

Oxidative stress and epigenetic regulation in ageing and age-related diseases

C Cencioni, F Spallotta, F Martelli, S Valente… - International journal of …, 2013 - mdpi.com
Recent statistics indicate that the human population is ageing rapidly. Healthy, but also
diseased, elderly people are increasing. This trend is particularly evident in Western …

Aging epigenetics: causes and consequences

C Huidobro, AF Fernandez, MF Fraga - Molecular Aspects of Medicine, 2013 - Elsevier
Growth and development of higher organisms are regulated by the orchestrated change of
epigenetic marks over time. In addition, there is also an epigenetic variation without any …

Epigenetics of aging and aging-related disease

A Brunet, SL Berger - Journals of Gerontology Series A …, 2014 - academic.oup.com
Aging is associated with a wide range of human disorders, including cancer, diabetes,
cardiovascular, and neurodegenerative diseases. Long thought to be an inexorable road …

Epigenetics and aging

S Pal, JK Tyler - Science advances, 2016 - science.org
Over the past decade, a growing number of studies have revealed that progressive changes
to epigenetic information accompany aging in both dividing and nondividing cells …