G protein-coupled receptors (GPCRs) represent the family of proteins with the highest
impact from social, therapeutic and economic point of view. Today, more than 50% of drug …

G protein-coupled receptors (GPCRs) represent the most abundant drug targets today. A
large number of GPCR-based drugs have already been developed for a variety of …

The broad range of G protein-coupled receptors (GPCRs) encompasses all areas of modern
medicine and have an enormous impact on the process of drug development. Using disease …

As one of the most successful therapeutic target families, G protein-coupled receptors
(GPCRs) have experienced a transformation from random ligand screening to knowledge …

Structural studies of G protein-coupled receptors (GPCRs) gave insights into molecular
mechanisms of their action and contributed significantly to molecular pharmacology. This is …

G protein-coupled receptors (GPCR) comprise a diverse superfamily of over 800 proteins
that have gained relevance as biological targets for pharmaceutical drug design. Although …

G protein-coupled receptors (GPCRs) are targets for 60–70% of drugs in development
today. Traditionally, the drug discovery process has relied on screening of chemical …

G protein-coupled receptors (GPCRs) represent one of the most important drug discovery
targets such that compounds targeted against GPCRs represent the single largest drug …

G-protein-coupled receptors (GPCRs) constitute a large family of structurally similar proteins
that respond to a chemically diverse array of physiological and environmental stimulants …

An understanding of the functional mechanisms of G-protein-coupled receptors (GPCRs) is
very important for GPCR-related drug design. We have developed an integrated GPCR …