D Silvério, R Gonçalves, R Appelberg, M Saraiva - MBio, 2021 - Am Soc Microbiol
ABSTRACT Interleukin-1 (IL-1) is a key player in the immune response to pathogens due to its role in promoting inflammation and recruiting immune cells to the site of infection. In …
Abstract The interleukin-10 (IL-10) family of cytokines consists of six immune mediators, namely IL-10, IL-19, IL-20, IL-22, IL-24 and IL-26. IL-10, IL-22, IL-24 and IL-26 are critical for …
AM Cooper, SA Khader - Immunological reviews, 2008 - Wiley Online Library
Tuberculosis (TB) results from an interaction between a potent immune response and a chronically persistent pathogen. The ability of Mycobacterium tuberculosis (Mtb) to induce a …
Failure of mice to produce IL-10 has no effect on the bacterial burden of Mycobacterium tuberculosis infection in the lungs over the first 4–5 months of the disease. We show here …
AM Cooper, A Solache, SA Khader - Current opinion in immunology, 2007 - Elsevier
Our understanding of the role of interleukin (IL)-12 in controlling tuberculosis has expanded because of increased interest in other members of the IL-12 family of cytokines. Recent data …
CH Ladel, C Blum, A Dreher, K Reifenberg… - Infection and …, 1997 - Am Soc Microbiol
Tuberculosis is a chronic infectious disease which causes major health problems globally. Acquired resistance is mediated by T lymphocytes and executed by activated macrophages …
IL-11 is multifunctional cytokine whose physiological role in the lungs during pulmonary tuberculosis (TB) is poorly understood. Here, using in vivo administration of specific …
GL Beamer, DK Flaherty, BD Assogba… - The Journal of …, 2008 - journals.aai.org
IL-10 is a potent immunomodulatory cytokine that affects innate and acquired immune responses. The immunological consequences of IL-10 production during pulmonary …
L Moreira-Teixeira, PS Redford… - The Journal of …, 2017 - journals.aai.org
Tuberculosis (TB), caused by Mycobacterium tuberculosis infection, is a leading cause of mortality and morbidity, causing∼ 1.5 million deaths annually. CD4+ T cells and several …