[HTML][HTML] Pharmacogenomic biomarkers and their applications in psychiatry

H Kam, H Jeong - Genes, 2020 - mdpi.com
Realizing the promise of precision medicine in psychiatry is a laudable and beneficial
endeavor, since it should markedly reduce morbidity and mortality and, in effect, alleviate the …

Pharmacogenomic biomarkers in neuropsychiatry: The path to personalized medicine in mental disorders

R Cacabelos - … , Endophenotypes and Genes: Molecular Genetic and …, 2009 - Springer
Neuropsychiatric disorders and dementia represent a major cause of disability and high cost
in developed societies. Most disorders of the central nervous system (CNS) share some …

[HTML][HTML] Precision psychiatry applications with pharmacogenomics: artificial intelligence and machine learning approaches

E Lin, CH Lin, HY Lane - International journal of molecular sciences, 2020 - mdpi.com
A growing body of evidence now suggests that precision psychiatry, an interdisciplinary field
of psychiatry, precision medicine, and pharmacogenomics, serves as an indispensable …

[PDF][PDF] Pharmacogenomics: A road ahead for precision medicine in psychiatry

AF Pardiñas, MJ Owen, JTR Walters - Neuron, 2021 - cell.com
Psychiatric genomics is providing insights into the nature of psychiatric conditions that in
time should identify new drug targets and improve patient care. Less attention has been paid …

[HTML][HTML] Pharmacogenomics in the treatment of mood disorders: strategies and opportunities for personalized psychiatry

AT Amare, KO Schubert, BT Baune - EPMA journal, 2017 - Springer
Personalized medicine (personalized psychiatry in a specific setting) is a new model
towards individualized care, in which knowledge from genomics and other omic pillars …

[HTML][HTML] Psychiatric pharmacogenomics in the age of neuroscience: promises and challenges

S Kose, M Cetin - Psychiatry and Clinical Psychopharmacology, 2018 - Taylor & Francis
Most psychiatric disorders including major depressive disorder (MDD), anxiety disorders,
bipolar disorder, obsessive-compulsive disorder(OCD), schizophrenia, autism, and attention …

Pharmacogenomics in psychiatry: implications for practice

TR Moore, AM Hill… - Recent patents on …, 2014 - ingentaconnect.com
Psychotropic medications are used for numerous psychiatric and neurologic disorders, and
are associated with in some cases life-threatening adverse effects, high acquisition costs …

How can we realize the promise of personalized antidepressant medicines?

F Holsboer - Nature Reviews Neuroscience, 2008 - nature.com
Personalized medication that is based on pharmacogenetic data has long been expected to
improve the efficacy of treatments for neurological and psychiatric disorders, including …

Pharmacogenomics in psychiatry: from therapeutic drug monitoring to genomic medicine

S Crettol, J de Leon, C Hiemke… - Clinical Pharmacology & …, 2014 - Wiley Online Library
Psychiatry is increasingly combining new pharmacogenomic findings with therapeutic drug
monitoring (TDM) to improve the safety and efficacy of pharmacotherapy. However, a …

[HTML][HTML] Pharmacogenomic characterization in bipolar spectrum disorders

S Fortinguerra, V Sorrenti, P Giusti, M Zusso, A Buriani - Pharmaceutics, 2019 - mdpi.com
The holistic approach of personalized medicine, merging clinical and molecular
characteristics to tailor the diagnostic and therapeutic path to each individual, is steadily …