[PDF][PDF] Dark CPD s and photocarcinogenesis: the party continues after the lights go out

ZA Abdel‐Malek, P Cassidy - 2015 - academia.edu
Exposure to solar UV radiation is the main cause for all forms of skin cancers, including
melanoma. UVB photons (290–320 nm wavelength) represent the most energetic and …

UVA Radiation, DNA damage, and melanoma

SG Jin, F Padron, GP Pfeifer - ACS omega, 2022 - ACS Publications
Melanoma is a lethal type of skin tumor that has been linked with sunlight exposure chiefly in
fair-skinned human populations. Wavelengths from the sun that can reach the earth's …

Ultraviolet radiation and melanomagenesis: from mechanism to immunotherapy

X Sun, N Zhang, C Yin, B Zhu, X Li - Frontiers in Oncology, 2020 - frontiersin.org
Melanoma is the deadliest form of skin cancer, and nearly 90% of melanomas are believed
to be caused by ultraviolet radiation (UVR), mainly from sunlight. UVR induces DNA …

UV wavelength-dependent DNA damage and human non-melanoma and melanoma skin cancer

GP Pfeifer, A Besaratinia - Photochemical & photobiological sciences, 2012 - pubs.rsc.org
Ultraviolet (UV) irradiation from the sun has been epidemiologically and mechanistically
linked to skin cancer, a spectrum of diseases of rising incidence in many human …

Commentary: Chemiexcitation of melanin derivatives induces DNA photoproducts long after UV exposure

RP Gajula, S Gaddameedhi - Frontiers in Physiology, 2015 - frontiersin.org
Cutaneous malignant melanoma (CMM) is one of the most rapidly increasing cancers in the
western world (Bowden, 2004). Frequency of its occurrence is closely associated with skin …

Skin pigmentation and melanoma risk

JA D'Orazio, A Marsch, J Veith - Advances in malignant …, 2011 - books.google.com
Malignant melanoma of the skin ranks as the number one cause of death from skin cancers.
Affecting over 125,000 people worldwide and nearly 70,000 persons annually in the United …

UV and skin: Photocarcinogenesis

ASW Oak, M Athar, N Yusuf, CA Elmets - Environment and Skin, 2018 - Springer
Because the annual incidence of nonmelanoma skin cancers (NMSCs), both basal cell
carcinomas and squamous cell carcinomas, exceeds that of all other cancers combined …

Chemiexcitation of melanin derivatives induces DNA photoproducts long after UV exposure

S Premi, S Wallisch, CM Mano, AB Weiner… - Science, 2015 - science.org
Mutations in sunlight-induced melanoma arise from cyclobutane pyrimidine dimers (CPDs),
DNA photoproducts that are typically created picoseconds after an ultraviolet (UV) photon is …

UV-induced melanin chemiexcitation: a new mode of melanoma pathogenesis

DE Brash - Toxicologic pathology, 2016 - journals.sagepub.com
Mutations in sunlight-induced melanoma arise from cyclobutane pyrimidine dimers (CPDs),
DNA photoproducts usually created picoseconds after an ultraviolet (UV) photon is …

Unanticipated role of melanin in causing carcinogenic cyclobutane pyrimidine dimers

S Premi, DE Brash - Molecular & cellular oncology, 2016 - Taylor & Francis
Ultraviolet radiation (UVR) instantaneously generates cyclobutane pyrimidine dimers
(CPDs). Paradoxically, we recently observed that UV enables the protective pigment …