High-density lipoproteins and cardiovascular disease: 2010 update

K Alwaili, Z Awan, A Alshahrani… - Expert review of …, 2010 - Taylor & Francis
High-density lipoprotein-cholesterol (HDL-C) is a continuous inverse cardiovascular risk
factor. The mechanisms by which HDLs protect against atherosclerosis are multiple. The …

Novel insights from human studies on the role of high-density lipoprotein in mortality and noncardiovascular disease

CM Madsen, A Varbo… - … , thrombosis, and vascular …, 2021 - Am Heart Assoc
The vast majority of research about HDL (high-density lipoprotein) has for decades revolved
around the possible role of HDL in atherosclerosis and its therapeutic potential within …

High-density lipoproteins: biology, epidemiology, and clinical management

HY Choi, A Hafiane, A Schwertani, J Genest - Canadian Journal of …, 2017 - Elsevier
High-density lipoproteins (HDLs) have multiple pleiotropic effects against arteriosclerosis.
Most are independent of the cholesterol mass within HDL particles. Yet, HDL cholesterol …

HDL and cardiovascular risk: time to call the plumber?

B Hewing, KJ Moore, EA Fisher - Circulation research, 2012 - Am Heart Assoc
High-density lipoprotein cholesterol (HDL-C) has been dubbed the good cholesterol
because it is thought to reflect the ability of HDL particles to remove excess cholesterol …

HDL, atherosclerosis, and emerging therapies

A Hafiane, J Genest - Cholesterol, 2013 - Wiley Online Library
This review aims to provide an overview on the properties of high‐density lipoproteins
(HDLs) and their cardioprotective effects. Emergent HDL therapies will be presented in the …

High-density lipoproteins: multifunctional vanguards of the cardiovascular system

M Marcil, B O'Connell, L Krimbou… - Expert review of …, 2004 - Taylor & Francis
The plasma level of high-density lipoprotein (HDL)-cholesterol is inversely correlated with
coronary artery disease, the leading cause of death worldwide. HDL particles are thought to …

High-density lipoprotein levels and risk of cardiovascular events: a review

GF Mureddu, F Brandimarte… - Journal of Cardiovascular …, 2012 - journals.lww.com
High-density lipoprotein cholesterol (HDL-C) is a strong and independent predictor of major
cardiovascular events in a wide range of patients. The relationship between HDL-C …

High-density lipoprotein: epidemiology, metabolism, and antiatherogenic effects

PP Toth - Disease-a-month, 2001 - Elsevier
Conclusion HDL is clearly a functionally versatile molecule mediating a variety of molecular
processes protective against atherosclerosis. Mechanistic detail continues to greatly enrich …

High density lipoproteins (HDLs) and atherosclerosis; the unanswered questions

P Barter, J Kastelein, A Nunn, R Hobbs, FFE Board - Atherosclerosis, 2003 - Elsevier
The concentration of high density lipoprotein-cholesterol (HDL-C) has been found
consistently to be a powerful negative predictor of premature coronary heart disease (CHD) …

High-density lipoproteins and atherosclerosis

DJ Rader - The American journal of cardiology, 2002 - Elsevier
High-density lipoproteins (HDLs) are strongly related to risk of atherosclerotic cardiovascular
disease. Low levels of HDL cholesterol are a major cardiovascular risk factor, and …