The transporter-mediated uptake of drugs from blood into hepatocytes is a prerequisite for
intrahepatic drug action or intracellular drug metabolism before excretion. Therefore, uptake …

Membrane transporters are now recognized as important determinants of the
transmembrane passage of drugs. Organic anion transporting polypeptides (OATP) form a …

Organic anion transporting polypeptide (OATP) family transporters accept a number of drugs
and are increasingly being recognized as important factors in governing drug and …

Members of the organic anion transporting polypeptide (OATP) transporter family are
involved in drug absorption and disposition, and therefore drug–drug and drug–food …

Members of the organic anion transporting polypeptide (OATP) family are responsible for the
cellular uptake of a broad range of endogenous compounds and xenobiotics in multiple …

Organic anion transporting polypeptides (OATP) 1B1 and OATP1B3 are important hepatic
transporters that mediate the uptake of many clinically important drugs, including statins from …

Organic anion transporting polypeptides (OATPs, gene family: SLC21/SLCO) mediate the
uptake of a broad range of substrates including several widely prescribed drugs into cells …

The importance of uptake transporters in determining drug disposition is increasingly
appreciated. While the focus of regulatory agencies worldwide has been on the hepatic …

The organic anion transporting polypeptide (OATP) 2B1 is localized on the basolateral
membrane of hepatocytes and is expressed in enterocytes. Based on its distribution pattern …

The importance of membrane transporters for drug pharmacokinetics has been increasingly
recognized during the last decade. Organic anion transporting polypeptide 1B1 (OATP1B1) …