IY Gong, RB Kim - Drug metabolism and pharmacokinetics, 2013 - jstage.jst.go.jp
There has been remarkable progress during the past decade in understanding of how genetic variations in drug metabolizing enzymes and transporters contribute to observed …
Y Shitara, K Maeda, K Ikejiri, K Yoshida… - … & drug disposition, 2013 - Wiley Online Library
Organic anion transporting polypeptide (OATP) family transporters accept a number of drugs and are increasingly being recognized as important factors in governing drug and …
M Niemi - Pharmacogenomics, 2007 - Taylor & Francis
During recent years, it has become increasingly recognized that drug transporters play important roles in drug absorption and disposition. Organic anion transporting polypeptides …
NF Smith, WD Figg, A Sparreboom - Expert opinion on drug …, 2005 - Taylor & Francis
Members of the organic anion transporting polypeptide (OATP) family are responsible for the cellular uptake of a broad range of endogenous compounds and xenobiotics in multiple …
A Kalliokoski, M Niemi - British journal of pharmacology, 2009 - Wiley Online Library
Membrane transporters are now recognized as important determinants of the transmembrane passage of drugs. Organic anion transporting polypeptides (OATP) form a …
Objective The uptake carrier organic anion-transporting polypeptide 1B3 (OATP1B3, gene SLCO1B3) is involved in the hepatic clearance of xenobiotics including statins, taxanes, and …
A Seithel, H Glaeser, MF Fromm… - Expert opinion on drug …, 2008 - Taylor & Francis
It is increasingly recognised that uptake transporters of the organic anion-transporting polypeptide (OATP) family play important roles in drug absorption, distribution and excretion …
The importance of membrane transporters for drug pharmacokinetics has been increasingly recognized during the last decade. Organic anion transporting polypeptide 1B1 (OATP1B1) …
RG Tirona, RB Kim - Advanced drug delivery reviews, 2002 - Elsevier
The organic anion-transporting polypeptides (OATP) represent a family of proteins responsible for the membrane transport of a large number of endogenous and xenobiotic …