Retrospective review of serum teicoplanin concentrations in clinical trials and their relationship to clinical outcome

A MacGowan, L White, D Reeves, I Harding - Journal of Infection and …, 1996 - Elsevier
Twenty-five published clinical studies were reviewed in which teicoplanin serum
concentrations were determined. A variety of assay methods were used, including bioassay …

Teicoplanin pharmacokinetics in healthy volunteers after administration of intravenous loading and maintenance doses

WR Outman, CH Nightingale… - Antimicrobial agents …, 1990 - Am Soc Microbiol
Teicoplanin is an investigational glycopeptide antibiotic that is structurally and
microbiologically similar to vancomycin. Since teicoplanin possesses a very long elimination …

Pharmacokinetics and tolerability of teicoplanin in healthy volunteers after single increasing doses

A Del Favero, L Patoia, R Rosina… - Antimicrobial agents …, 1991 - Am Soc Microbiol
In this double-blind, randomized study, five healthy subjects per group received doses of 15,
20, or 25 mg of teicoplanin per kg of body weight, and one subject per group received a …

Randomized comparison of serum teicoplanin concentrations following daily or alternate daily dosing in healthy adults

B Rouveix, F Jehl, H Drugeon, I Brumpt… - Antimicrobial agents …, 2004 - Am Soc Microbiol
Trough serum teicoplanin concentrations were compared in healthy adults following
intravenous administration of one of two regimens:(i) 12 mg/kg of body weight every 12 h for …

Therapeutic drug concentrations of teicoplanin in clinical settings

SY Nah, JH Im, JY Yeo, JH Baek… - Infection & …, 2014 - synapse.koreamed.org
Background Teicoplanin is a glycopeptide antibiotic that is widely used in clinical practice for
the treatment of infections caused by drug-resistant Gram-positive bacteria. The aim of this …

Pharmacokinetics of teicoplanin upon multiple-dose intravenous administration of 3, 12, and 30 milligrams per kilogram of body weight to healthy male volunteers

JA Smithers, HK Kulmala, GA Thompson… - Antimicrobial agents …, 1992 - Am Soc Microbiol
Teicoplanin pharmacokinetics were evaluated after multiple-dose intravenous
administration to healthy male volunteers by using a randomized, double-blind, parallel …

Factors on trough teicoplanin levels, associations between levels, efficacy and safety in patients with gram-positive infections.

T Wang, N Li, S Hu, J Xie, J Lei, Y Wang… - … Journal of Clinical …, 2015 - europepmc.org
Objective The objective of this study was to identify the factors influencing trough teicoplanin
concentrations (C (min)), to investigate the relationship between teicoplanin C (min) with …

[HTML][HTML] Pharmacokinetics of teicoplanin during plasma exchange

P Akt, O Lortholary, F Fauvelle, M Tod… - Clinical microbiology …, 1999 - Elsevier
Objective To study the elimination of teicoplanin during plasma exchange, a procedure
currently used to treat a variety of disorders involving immune complexes. Teicoplanin is a …

Analyses of teicoplanin concentrations from 1994 to 2006 from a UK assay service

CM Tobin, AM Lovering, E Sweeney… - Journal of …, 2010 - academic.oup.com
Objectives An analysis of the trough serum concentrations sent to the UK Antimicrobial
Reference Laboratory for teicoplanin therapeutic drug monitoring (TDM). Methods All trough …

Clinical efficacy and safety of teicoplanin

W Stille, W Sietzen, HA Dieterich… - Journal of Antimicrobial …, 1988 - academic.oup.com
This was an open efficacy and safety study in 310 hospitalized patients (187 male and 123
female) with infection by Gram-positive bacteria. The age range was 12–88 years (mean 49 …