Chronic heart failure affects myocardial energy metabolism and cardiac function. Puerarin
has been reported to improve cardiac function through regulation of energy metabolism in …

Myocardial infarction (MI) causes disturbances in myocardial energy metabolism, ultimately
leading to a poor prognosis. Cytosolic glycogen autophagy (glycophagy) and mitochondrial …

New Findings What is the central question of this study? Does the advanced glycation end
products (AGEs)–receptor for advanced glycation end products (RAGE) axis mediate …

Xuesaitong injection (XST), which mainly consists of Panax notoginseng saponins, has
been widely used for treating cardio-cerebral vascular diseases. However, the underlying …

Cardiomyocytes are particularly prone to lipofuscin accumulation. In the aging heart,
lipofuscin accumulation is augmented. This study examined distribution of lipofuscin and …

Cardiac fibrosis is a common pathophysiological process observed during chronic and
stress‐induced acceleration of cardiac aging. Fibrosis is a necessary process during wound …

Objective To investigate whether ginsenoside-Rb1 (Gs-Rb1) improves the CoCl-induced
autophagy of cardiomyocytes via upregulation of adenosine 5′-monophosphate-activated …

The dysregulation of autophagy is associated with a series of cardiovascular diseases, such
as myocardial ischemia injury. Lactone component from Ligusticum chuanxiong (LLC) is the …

Background Mitochondrial dysfunction is an important pathological feature of chronic heart
failure (CHF). Regulation of mitophagy can effectively maintain mitochondrial homeostasis …

Abstract Astragaloside IV (AS-IV), the major active constituent purified from Astragalus
membranaceus, was previously reported to have protective effects against cardiac …