Parkinson's disease (PD) is the second most common neurodegenerative disease
worldwide, classically characterized by a triad of motor features: bradykinesia, rigidity and …

The characteristic and selective degeneration of a unique population of cells—the
nigrostriatal dopamine (DA) neurons—that occurs in Parkinson's disease (PD) has made the …

In Parkinson's disease (PD), the main pathology is a loss of nigrostriatal dopamine (DA)
neurons. Clinical trials with intrastriatal transplantation of human embryonic mesencephalic …

Cell replacement therapy has been proposed as a means to replace lost dopaminergic
neurons in Parkinson's disease (PD). In most studies, the transplanted cells have been …

Curative therapies or treatments reversing the progression of Parkinson's disease (PD) have
attracted considerable interest in the last few decades. PD is characterized by the gradual …

Parkinson disease (PD) is characterized by loss of the A9 nigral neurons that provide
dopaminergic innervation to the striatum. This discovery led to the successful instigation of …

Parkinson's disease (PD) is a chronic progressive neurodegenerative disorder
symptomatically characterized by resting tremor, rigidity, bradykinesia, and gait impairment …

Over the past three decades, significant progress has been made in the development of
potential regenerative cell-based therapies for neurodegenerative disease, with most …

Abstract Parkinson's disease (PD), one of the most frequent neurodegenerative disorders, is
primarily caused by the selective degeneration of specific neuronal populations, particularly …

Parkinson's disease (PD) is a neurodegenerative disorder caused by the loss of neurons in
the substantia nigra pars compacta and a striatal deficiency of dopamine. PD typically affects …