From NASH to HCC: current concepts and future challenges

QM Anstee, HL Reeves, E Kotsiliti, O Govaere… - Nature reviews …, 2019 - nature.com
Caloric excess and sedentary lifestyle have led to a global epidemic of obesity and
metabolic syndrome. The hepatic consequence of metabolic syndrome and obesity …

NAFLD-associated HCC: progress and opportunities

D Geh, QM Anstee, HL Reeves - Journal of Hepatocellular …, 2021 - Taylor & Francis
Due to an increase in the obesity-associated metabolic syndrome of epidemic proportions,
nonalcoholic fatty liver disease (NAFLD) is becoming a leading cause of hepatocellular …

NAFLD-driven HCC: Safety and efficacy of current and emerging treatment options

F Foerster, SJ Gairing, L Müller, PR Galle - Journal of hepatology, 2022 - Elsevier
In light of a global rise in obesity and type 2 diabetes, non-alcoholic fatty liver disease
(NAFLD) and non-alcoholic steatohepatitis (NASH) represent an increasingly important …

Role of immune responses in the development of NAFLD-associated liver cancer and prospects for therapeutic modulation

N Yahoo, M Dudek, P Knolle, M Heikenwälder - Journal of Hepatology, 2023 - Elsevier
The liver is the central metabolic organ of the body, regulating energy and lipid metabolism,
while also having potent immunological functions. Overwhelming the metabolic capacity of …

[HTML][HTML] Molecular links between non-alcoholic fatty liver disease and hepatocellular carcinoma

S Raza, S Rajak, B Anjum, RA Sinha - Hepatoma research, 2019 - ncbi.nlm.nih.gov
Non-alcoholic fatty liver disease (NAFLD) and its advanced complication, non-alcoholic
steatohepatitis (NASH), have become leading causes of hepatocellular carcinoma (HCC) …

[HTML][HTML] Nonalcoholic fatty liver disease, metabolic risk factors, and hepatocellular carcinoma: an open question

LAM Streba, CC Vere, I Rogoveanu… - World journal of …, 2015 - ncbi.nlm.nih.gov
Non-alcoholic liver disease (NAFLD) defines liver abnormalities ranging from simple
steatosis to nonalcoholic steatohepatitis with or without cirrhosis development, occurring in …

[HTML][HTML] Non-alcoholic fatty liver disease and hepatocellular carcinoma: Clinical challenges of an intriguing link

L Chrysavgis, I Giannakodimos… - World Journal of …, 2022 - ncbi.nlm.nih.gov
Non-alcoholic fatty liver disease (NAFLD) has emerged as the most common liver disorder
worldwide mainly attributed to the epidemic spread of obesity and type 2 diabetes mellitus …

NAFLD, NASH and liver cancer

GA Michelotti, MV Machado, AM Diehl - … reviews Gastroenterology & …, 2013 - nature.com
NAFLD affects a large proportion of the US population and its incidence and prevalence are
increasing to epidemic proportions around the world. As with other liver diseases that cause …

Epidemiology and risk-stratification of NAFLD-associated HCC

GN Ioannou - Journal of hepatology, 2021 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is projected to become the leading cause of
hepatocellular carcinoma (HCC) in many countries. Many risk factors for NAFLD are also …

Hepatocellular carcinoma and non-alcoholic fatty liver disease

P Golabi, L Rhea, L Henry, ZM Younossi - Hepatology international, 2019 - Springer
Nonalcoholic fatty liver disease (NAFLD) is considered the most common liver disorder
worldwide, affecting 25.2% of the general population. In fact, NAFLD is among the most …