A recombinant vesicular stomatitis virus-based Lassa fever vaccine protects guinea pigs and macaques against challenge with geographically and genetically distinct …
D Safronetz, C Mire, K Rosenke… - PLoS neglected …, 2015 - journals.plos.org
Background Lassa virus (LASV) is endemic in several West African countries and is the
etiological agent of Lassa fever. Despite the high annual incidence and significant morbidity …
etiological agent of Lassa fever. Despite the high annual incidence and significant morbidity …
A recombinant VSV-vectored vaccine rapidly protects nonhuman primates against heterologous lethal Lassa fever
Lassa virus (LASV) is recognized by the World Health Organization as one of the top five
pathogens likely to cause a severe outbreak. A recent unprecedented resurgence of LASV …
pathogens likely to cause a severe outbreak. A recent unprecedented resurgence of LASV …
A recombinant vesicular stomatitis-based Lassa fever vaccine elicits rapid and long-term protection from lethal Lassa virus infection in guinea pigs
Abstract The World Health Organization has identified Lassa virus (LASV) as one of the top
five pathogens to cause a severe outbreak in the near future. This study assesses the ability …
five pathogens to cause a severe outbreak in the near future. This study assesses the ability …
Development of a new vaccine for the prevention of Lassa fever
TW Geisbert, S Jones, EA Fritz, AC Shurtleff… - PLoS …, 2005 - journals.plos.org
Background Recent importation of Lassa fever into Germany, the Netherlands, the United
Kingdom, and the United States by travelers on commercial airlines from Africa underscores …
Kingdom, and the United States by travelers on commercial airlines from Africa underscores …
Baseline mapping of Lassa fever virology, epidemiology and vaccine research and development
HJ Hallam, S Hallam, SE Rodriguez, ADT Barrett… - NPJ vaccines, 2018 - nature.com
Lassa fever (LF) is a zoonotic disease associated with acute and potentially fatal
hemorrhagic illness caused by the Lassa virus (LASV), a member of the family Arenaviridae …
hemorrhagic illness caused by the Lassa virus (LASV), a member of the family Arenaviridae …
Pathogenicity and virulence mechanisms of Lassa virus and its animal modeling, diagnostic, prophylactic, and therapeutic developments
HL Murphy, H Ly - Virulence, 2021 - Taylor & Francis
Lassa fever (LF) is a deadly viral hemorrhagic disease that is endemic to West Africa. The
causative agent of LF is Lassa virus (LASV), which causes approximately 300,000 infections …
causative agent of LF is Lassa virus (LASV), which causes approximately 300,000 infections …
Animal models of lassa fever
Lassa virus (LASV), the causative agent of Lassa fever, is estimated to be responsible for up
to 300,000 new infections and 5000 deaths each year across Western Africa. The most …
to 300,000 new infections and 5000 deaths each year across Western Africa. The most …
Advanced vaccine candidates for Lassa fever
IS Lukashevich - Viruses, 2012 - mdpi.com
Lassa virus (LASV) is the most prominent human pathogen of the Arenaviridae. The virus is
transmitted to humans by a rodent reservoir, Mastomys natalensis, and is capable of causing …
transmitted to humans by a rodent reservoir, Mastomys natalensis, and is capable of causing …
The search for animal models for Lassa fever vaccine development
IS Lukashevich - Expert review of vaccines, 2013 - Taylor & Francis
Lassa virus (LASV) is the most prevalent arenavirus in West Africa and is responsible for
several hundred thousand infections and thousands of deaths annually. The sizeable …
several hundred thousand infections and thousands of deaths annually. The sizeable …
A Lassa fever live-attenuated vaccine based on codon deoptimization of the viral glycoprotein gene
Lassa virus (LASV) is endemic in Western Africa and is estimated to infect hundreds of
thousands of individuals annually. A considerable number of these infections result in Lassa …
thousands of individuals annually. A considerable number of these infections result in Lassa …