Various toxic compounds produce reactive oxygen species, resulting in oxidative stress that
threatens cellular homeostasis. Yet, lower doses of stress can stimulate defence systems …

Hyperthermia is a promising anticancer treatment used in combination with radiotherapy
and chemotherapy. Temperatures above 41.5° C are cytotoxic and hyperthermia treatments …

Preexposure to mild temperatures such as 40° C induces thermotolerance, whereby cells
resist subsequent exposure to a toxic insult. This study investigates the protective effect of …

Autophagy is a self-digestion process that degrades intracellular structures in response to
stresses leading to cell survival. When autophagy is prolonged, this could lead to cell death …

The exposure to low doses of stress induces an adaptive survival response that involves
upregulation of cellular defense systems such as heat shock proteins (Hsp), anti-apoptosis …

Protein homeostasis or proteostasis, the correct balance between production and
degradation of proteins, is an essential pillar for proper cellular function. Among the several …

Exposure of cells to mild temperatures (40° C) induces thermotolerance, which renders cells
resistant to subsequent toxic insults. Thermotolerance is usually associated with …

Accumulation of reactive oxygen species (ROS) such as hydrogen peroxide (H2O2) is an
oxidative stress response, which induced various defense mechanisms or programmed cell …

The occurrence and mechanisms of autophagy induced by heat stress are not well known in
lung cancer cells. Here, we have demonstrated that heat stress induces autophagy in A549 …

Cancer cells are characterised by uncontrolled cell proliferation; however, some of them can
temporarily arrest their cell cycle at the G0 or G1 phase, which could contribute to tumour …