[HTML][HTML] Rapid development of neutralizing and diagnostic SARS-COV-2 mouse monoclonal antibodies

AP Chapman, X Tang, JR Lee, A Chida, K Mercer… - Scientific Reports, 2021 - nature.com
The need for high-affinity, SARS-CoV-2-specific monoclonal antibodies (mAbs) is critical in
the face of the global COVID-19 pandemic, as such reagents can have important diagnostic …

[HTML][HTML] A therapeutic neutralizing antibody targeting receptor binding domain of SARS-CoV-2 spike protein

C Kim, DK Ryu, J Lee, YI Kim, JM Seo, YG Kim… - Nature …, 2021 - nature.com
Vaccines and therapeutics are urgently needed for the pandemic caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2). Here, we screen human monoclonal …

[HTML][HTML] Isolation and characterization of neutralizing monoclonal antibodies from a large panel of murine antibodies against RBD of the SARS-CoV-2 Spike protein

E D'Acunto, A Muzi, S Marchese, L Donnici, V Chiarini… - Antibodies, 2024 - mdpi.com
The COVID-19 pandemic, once a global crisis, is now largely under control, a testament to
the extraordinary global efforts involving vaccination and public health measures. However …

[PDF][PDF] The neutralization potency of anti-SARS-CoV-2 therapeutic human monoclonal antibodies is retained against viral variants

E Makdasi, A Zvi, R Alcalay, T Noy-Porat, E Peretz… - Cell Reports, 2021 - cell.com
A wide range of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
neutralizing monoclonal antibodies (mAbs) have been reported, most of which target the …

Neutralizing antibodies targeting the SARS‐CoV‐2 receptor binding domain isolated from a naïve human antibody library

BN Bell, AE Powell, C Rodriguez, JR Cochran… - Protein …, 2021 - Wiley Online Library
Infection with SARS‐CoV‐2 elicits robust antibody responses in some patients, with a
majority of the response directed at the receptor binding domain (RBD) of the spike surface …

[PDF][PDF] Structural mechanism of SARS-CoV-2 neutralization by two murine antibodies targeting the RBD

JM Errico, H Zhao, RE Chen, Z Liu, JB Case, M Ma… - Cell Reports, 2021 - cell.com
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has
necessitated the rapid development of antibody-based therapies and vaccines as …

[HTML][HTML] Monoclonal antibodies specific for SARS-CoV-2 spike protein suitable for multiple applications for current variants of concern

MS Morgan, K Yan, TT Le, RA Johnston, AA Amarilla… - Viruses, 2022 - mdpi.com
The global coronavirus disease 2019 (COVID-19) pandemic caused by the severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) has spawned an ongoing demand for …

[HTML][HTML] A panel of human neutralizing mAbs targeting SARS-CoV-2 spike at multiple epitopes

T Noy-Porat, E Makdasi, R Alcalay, A Mechaly… - Nature …, 2020 - nature.com
The novel highly transmissible human coronavirus SARS-CoV-2 is the causative agent of
the COVID-19 pandemic. Thus far, there is no approved therapeutic drug specifically …

[HTML][HTML] Identification of potent human neutralizing antibodies against SARS-CoV-2 implications for development of therapeutics and prophylactics

S Zhao, H Zhang, X Yang, H Zhang, Y Chen… - Nature …, 2021 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel coronavirus that
is spreading rapidly, which seriously impacts global public health and economy. Thus …

[HTML][HTML] Generation and characterization of a multi-functional panel of monoclonal antibodies for SARS-CoV-2 research and treatment

LD Patterson, BD Dubansky, BH Dubansky, S Stone… - Viruses, 2023 - mdpi.com
The Coronavirus disease 2019 (COVID-19) pandemic caused by Severe Acute Respiratory
Syndrome-Coronavirus-2 (SARS-CoV-2) is an ongoing threat to global public health. To this …