Use of corticosteroids in acute lung injury and acute respiratory distress syndrome: a systematic review and meta-analysis

BMP Tang, JC Craig, GD Eslick, I Seppelt… - Critical care …, 2009 - journals.lww.com
Objective: Controversy remains as to whether low-dose corticosteroids can reduce the
mortality and morbidity of acute lung injury (ALI) or the acute respiratory distress syndrome …

Corticosteroid therapy for acute lung injury, acute respiratory distress syndrome, and severe pneumonia: a meta-analysis of randomized controlled trials

F Lamontagne, M Briel, GH Guyatt, DJ Cook… - Journal of critical …, 2010 - Elsevier
BACKGROUND: Randomized trials investigating the effect of corticosteroids in the treatment
of acute lung injury, acute respiratory distress syndrome, and severe pneumonia have had …

Exploring the heterogeneity of effects of corticosteroids on acute respiratory distress syndrome: a systematic review and meta-analysis

SY Ruan, HH Lin, CT Huang, PH Kuo, HD Wu, CJ Yu - Critical care, 2014 - Springer
Introduction The effectiveness of corticosteroid therapy on the mortality of acute respiratory
distress syndrome (ARDS) remains under debate. We aimed to explore the grounds for the …

[PDF][PDF] Corticosteroids for patients with acute respiratory distress syndrome: a systematic review and meta-analysis of randomized trials

MJ Mammen, K Aryal, W Alhazzani… - Pol Arch Intern …, 2020 - scholar.archive.org
ABSTRACT INTRODUCTION Acute respiratory distress syndrome (ARDS) is a rapidly
progressing, inflammatory lung disease with a high mortality rate and no specific …

Steroid treatment in ARDS: a critical appraisal of the ARDS network trial and the recent literature

GU Meduri, PE Marik, GP Chrousos, SM Pastores… - Intensive care …, 2008 - Springer
Objectives To compare the design and results of randomized trials investigating prolonged
glucocorticoid treatment (≥ 7 days) in patients with acute lung injury–acute respiratory …

Do glucocorticoids decrease mortality in acute respiratory distress syndrome? A meta‐analysis

R Agarwal, A Nath, AN Aggarwal, D Gupta - Respirology, 2007 - Wiley Online Library
Background and objectives: Glucocorticoids have been shown to improve survival when
used in patients with septic shock. The aim of this study was to analyse the role of …

Glucocorticoid treatment in acute lung injury and acute respiratory distress syndrome

PE Marik, GU Meduri, PRM Rocco… - Critical care …, 2011 - criticalcare.theclinics.com
The acute respiratory distress syndrome (ARDS) is a common and vexing problem faced by
critical care providers worldwide. Despite extensive investigation over the past 3 decades …

Corticosteroids in the prevention and treatment of acute respiratory distress syndrome (ARDS) in adults: meta-analysis

JV Peter, P John, PL Graham, JL Moran, IA George… - Bmj, 2008 - bmj.com
Objective To systematically review the efficacy of steroids in the prevention of acute
respiratory distress syndrome (ARDS) in critically ill adults, and treatment for established …

Prolonged low-dose methylprednisolone treatment is highly effective in reducing duration of mechanical ventilation and mortality in patients with ARDS

GU Meduri, RAC Siemieniuk, RA Ness… - Journal of Intensive …, 2018 - Springer
An updated meta-analysis incorporating nine randomized trials (n= 816) investigating low-to-
moderate dose prolonged glucocorticoid treatment in acute respiratory distress syndrome …

Effect of low doses of corticosteroids in septic shock patients with or without early acute respiratory distress syndrome

D Annane, V Sébille, E Bellissant… - Critical care …, 2006 - journals.lww.com
Objective: We investigated the efficacy of low doses of corticosteroids in septic shock
patients with or without early acute respiratory distress syndrome (ARDS) by post hoc …