Peroxisome proliterator-activated receptor-alpha activators regulate genes governing lipoprotein metabolism, vascular inflammation and atherosclerosis

JC Fruchart, P Duriez, B Staels - Current opinion in lipidology, 1999 - journals.lww.com
The peroxisome proliferator-activated receptors (PPARs)[alpha, delta (beta) and gamma]
form a subfamily of the nuclear receptor gene family. All PPARs are, albeit to different …

[HTML][HTML] Is there a future for PPARs in the treatment of neuropsychiatric disorders?

M Tufano, G Pinna - Molecules, 2020 - mdpi.com
Recently, peroxisome proliferator-activated receptor (PPAR)-α and γ isoforms have been
gaining consistent interest in neuropathology and treatment of neuropsychiatric disorders …

The peroxisome proliferator‐activated receptors in cardiovascular diseases: experimental benefits and clinical challenges

WS Cheang, XY Tian, WT Wong… - British journal of …, 2015 - Wiley Online Library
The peroxisome proliferator‐activated receptors, PPAR α, PPAR β/δ and PPAR γ, are ligand‐
activated transcriptional factors belonging to the nuclear receptors superfamily and they are …

[HTML][HTML] Role of phytoconstituents as PPAR agonists: implications for neurodegenerative disorders

A Sharma, HJ Lee - Biomedicines, 2021 - mdpi.com
Peroxisome proliferator-activated receptors (PPAR-γ, PPAR-α, and PPAR-β/δ) are ligand-
dependent nuclear receptors that play a critical role in the regulation of hundreds of genes …

[HTML][HTML] Peroxisome proliferator-activated receptors (PPARs) and oxidative stress in physiological conditions and in cancer

G Muzio, G Barrera, S Pizzimenti - Antioxidants, 2021 - mdpi.com
Peroxisome proliferator-activated receptors (PPARs) belong to the nuclear hormone
receptor superfamily. Originally described as “orphan nuclear receptors”, they can bind both …

[PDF][PDF] Eurosterone Meeting–Peroxisome proliferator-activated receptors in inflammation control

P Delerive, JC Fruchart, B Staels - J Endocrinol, 2001 - scholar.archive.org
Peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription
factors belonging to the nuclear receptor superfamily. PPARα is highly expressed in liver …

Roles of peroxisome proliferator-activated receptor delta (PPARδ) in the control of fatty acid catabolism. A new target for the treatment of metabolic syndrome

S Luquet, J Lopez-Soriano, D Holst, C Gaudel… - Biochimie, 2004 - Elsevier
Peroxisome proliferator-activated receptors (PPARs) are lipid-activated transcription factors
playing important regulatory functions in development and metabolism. PPARα and PPARγ …

[HTML][HTML] The peroxisome proliferator-activated receptor: A family of nuclear receptors role in various diseases

S Tyagi, P Gupta, AS Saini, C Kaushal… - Journal of advanced …, 2011 - journals.lww.com
Peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription
factors of nuclear hormone receptor superfamily comprising of the following three subtypes …

[HTML][HTML] PPARγ and PGC-1α as therapeutic targets in Parkinson's

JC Corona, MR Duchen - Neurochemical research, 2015 - Springer
The peroxisome proliferator-activated receptor gamma (PPARγ) is a ligand-activated
transcriptional factor that belongs to the nuclear hormone receptor superfamily. PPARγ was …

From molecular action to physiological outputs: peroxisome proliferator-activated receptors are nuclear receptors at the crossroads of key cellular functions

JN Feige, L Gelman, L Michalik, B Desvergne… - Progress in lipid …, 2006 - Elsevier
Peroxisome proliferator-activated receptors (PPARs) compose a family of three nuclear
receptors which act as lipid sensors to modulate gene expression. As such, PPARs are …