Maternal immune activation (mIA) during pregnancy is hypothesised to disrupt offspring neurodevelopment and predispose offspring to neurodevelopmental disorders such as …
E Minakova, BB Warner - Birth defects research, 2018 - Wiley Online Library
Maternal immune activation (MIA) refers to a maternal immune system triggered by infectious or infectious‐like stimuli. A cascade of cytokines and immunologic alterations are …
Growing evidence from epidemiological studies strongly suggests maternal infection as a risk factor for psychiatric disorders including bipolar disorder, schizophrenia, and autism …
MB Hall, DE Willis, EL Rodriguez… - Frontiers in …, 2023 - frontiersin.org
Epidemiological evidence suggests that one's risk of being diagnosed with a neurodevelopmental disorder (NDD)—such as autism, ADHD, or schizophrenia—increases …
AS Brown, U Meyer - American Journal of Psychiatry, 2018 - Am Psychiatric Assoc
Epidemiologic studies, including prospective birth cohort investigations, have implicated maternal immune activation in the etiology of neuropsychiatric disorders. Maternal infectious …
ML Estes, AK McAllister - Science, 2016 - science.org
Epidemiological evidence implicates maternal infection as a risk factor for autism spectrum disorder and schizophrenia. Animal models corroborate this link and demonstrate that …
HK Kwon, GB Choi, JR Huh - Trends in immunology, 2022 - cell.com
Exposure to heightened inflammation in pregnancy caused by infections or other inflammatory insults has been associated with the onset of neurodevelopmental and …
Converging lines of evidence from basic science and clinical studies suggest a relationship between maternal immune activation (MIA) and neurodevelopmental disorders such as …
MC Bucknor, A Gururajan, RC Dale… - Frontiers in …, 2022 - frontiersin.org
Prenatal brain development is a highly orchestrated process, making it a very vulnerable window to perturbations. Maternal stress and subsequent inflammation during pregnancy …