Regulation of gene expression requires dynamic changes in chromatin, but the nature of
these changes is not well understood. Here, we show that progesterone treatment of …

Transcription from the mouse mammary tumor virus (MMTV) promoter can be induced by
glucocorticoids or progestins. Progesterone treatment of cultured cells carrying an integrated …

SWI-SNF is an ATP-dependent chromatin remodeling complex that disrupts DNA-histone
interactions. Several studies of SWI-SNF activity on mononucleosome substrates have …

Chromatin, a combination of nucleosomes and linker histones, inhibits transcription by
blocking polymerase movement and access of factors to DNA. ATP-dependent remodeling …

The ATP-dependent chromatin remodeling complex SWI/SNF regulates transcription and
has been implicated in promoter nucleosome eviction. Efficient nucleosome disassembly by …

ABSTRACT SWI/SNF is a well-characterized chromatin remodeling complex that remodels
chromatin by sliding nucleosomes in cis and/or displacing nucleosomes in trans. The latter …

Chromatin remodeling enzymes use the energy of ATP hydrolysis to alter histone–DNA
contacts and regulate DNA-based processes in eukaryotes. Whether different subfamilies of …

SWI-SNF is an ATP-dependent chromatin remodeling complex required for expression of a
number of yeast genes. Previous studies have suggested that SWI-SNF action may remove …

We utilized a site-specific cross-linking technique to investigate the mechanism of
nucleosome remodeling by hSWI/SNF. We found that a single cross-link between H2B and …

The physical structure and the compact nature of the eukaryotic genome present a functional
barrier for any cellular process that requires access to the DNA. The linker histone H1 is …