Cytokine storm and leukocyte changes in mild versus severe SARS-CoV-2 infection: Review of 3939 COVID-19 patients in China and emerging pathogenesis and …

J Wang, M Jiang, X Chen… - Journal of Leucocyte …, 2020 - academic.oup.com
Clinical evidence indicates that the fatal outcome observed with severe acute respiratory
syndrome-coronavirus-2 infection often results from alveolar injury that impedes airway …

The role of IL-6 and other mediators in the cytokine storm associated with SARS-CoV-2 infection

A Copaescu, O Smibert, A Gibson, EJ Phillips… - Journal of Allergy and …, 2020 - Elsevier
The coronavirus disease 2019 pandemic caused by severe acute respiratory syndrome
coronavirus 2 presents with a spectrum of clinical manifestations from asymptomatic or mild …

Dysregulation of the immune response in coronavirus disease 2019

L Mohamed Khosroshahi, N Rezaei - Cell Biology International, 2021 - Wiley Online Library
Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) can trigger a cytokine
storm in the pulmonary tissue by releasing various types of mediators, leading to acute …

SARS‐CoV‐2‐mediated immune system activation and potential application in immunotherapy

Y Tan, F Tang - Medicinal research reviews, 2021 - Wiley Online Library
Although novel severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2)‐mediated
pulmonary inflammation has recently attracted great attention, its pathology and …

Early risk factors for the duration of severe acute respiratory syndrome coronavirus 2 viral positivity in patients with coronavirus disease 2019

A Lin, ZB He, S Zhang, JG Zhang… - Clinical Infectious …, 2020 - academic.oup.com
Background Pneumonia coronavirus disease 2019 (COVID-19) has became a pandemic.
However, information on early risk factors for the duration of severe acute respiratory …

Respiratory and systemic monocytes, dendritic cells, and myeloid‐derived suppressor cells in COVID‐19: Implications for disease severity

S Falck‐Jones, B Österberg… - Journal of Internal …, 2023 - Wiley Online Library
Since the beginning of the SARS‐CoV‐2 pandemic in 2020, researchers worldwide have
made efforts to understand the mechanisms behind the varying range of COVID‐19 disease …

Suppressed T cell-mediated immunity in patients with COVID-19: a clinical retrospective study in Wuhan, China

XU Bo, C Fan, A Wang, Y Zou, Y Yu, HE Cong, W Xia… - Journal of Infection, 2020 - Elsevier
Importance An ongoing outbreak of COVID-19 has exhibited significant threats around the
world. We found a significant decrease of T lymphocyte subsets and an increase of …

T cell responses are required for protection from clinical disease and for virus clearance in severe acute respiratory syndrome coronavirus-infected mice

J Zhao, J Zhao, S Perlman - Journal of virology, 2010 - Am Soc Microbiol
ABSTRACT A dysregulated innate immune response and exuberant cytokine/chemokine
expression are believed to be critical factors in the pathogenesis of severe acute respiratory …

[HTML][HTML] Persistence of SARS CoV-2 S1 protein in CD16+ monocytes in post-acute sequelae of COVID-19 (PASC) up to 15 months post-infection

BK Patterson, EB Francisco, R Yogendra… - Frontiers in …, 2022 - frontiersin.org
The recent COVID-19 pandemic is a treatment challenge in the acute infection stage but the
recognition of chronic COVID-19 symptoms termed post-acute sequelae SARS-CoV-2 …

[HTML][HTML] A comprehensive review of coronavirus disease 2019: epidemiology, transmission, risk factors, and international responses

H Li, SW Burm, SH Hong, R Abou Ghayda… - Yonsei medical …, 2021 - ncbi.nlm.nih.gov
Abstract Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), has caused a worldwide pandemic. The first reports …