Background & Aims The contribution of genetic factors to the pathogenesis of inflammatory
bowel disease (IBD) has been established by twin, targeted-sequencing, and genome-wide …

Recent studies have greatly improved our insight into the genetic background of
inflammatory bowel disease (IBD). New high‐throughput technologies and large‐scale …

More than 240 genetic risk loci have been associated with inflammatory bowel disease
(IBD), but little is known about how they contribute to disease development in involved …

Over the past two decades, investigators have used whole genome linkage and genome-
wide association studies, including the “Immunochip” study, to identify a surprising number …

Abstract Background and Aims Genome-wide association studies [GWAS] for inflammatory
bowel disease [IBD] have identified 240 risk variants. However, the benefit of understanding …

Inflammatory bowel diseases (IBDs) are complex, multifactorial disorders that comprise
Crohn's disease (CD) and ulcerative colitis (UC). Genome-wide association studies have …

Inflammatory bowel diseases (IBDs) are complex, multifactorial disorders characterized by
chronic relapsing intestinal inflammation. Although etiology remains largely unknown, recent …

GWAS have identified> 200 risk loci for Inflammatory Bowel Disease (IBD). The majority of
disease associations are known to be driven by regulatory variants. To identify the putative …

In this review, we provide an update on genome-wide association studies (GWAS) in
inflammatory bowel disease (IBD). In addition, we summarize progress in defining the …

Regardless of how inflammatory bowel disease (IBD) is defined, the term “genetic
susceptibility” is always included. Due to substantial progress in the characterization of …