Novel chitosan-coated niosomal formulation for improved management of bacterial conjunctivitis: a highly permeable and efficient ocular nanocarrier for azithromycin

HM Eid, IA Naguib, RI Alsantali, I Alsalahat… - Journal of …, 2021 - Elsevier
In the present study, we aimed to formulate, optimize, and characterize azithromycin
chitosan coated niosomes (AZM-CTS-NSM) as a novel colloidal system that increases …

Formulation of Chitosan Polymeric Vesicles of Ciprofloxacin for Ocular Delivery: Box-Behnken Optimization, In Vitro Characterization, HET-CAM Irritation, and …

Ameeduzzafar, NK Alruwaili, SS Imam, NH Alotaibi… - AAPS …, 2020 - Springer
Ciprofloxacin is a commonly used antibiotic for treatment of bacterial conjunctivitis. The
conventional eye drop dosage form is the widely used mode of treatment, but it has low …

Clarithromycin-loaded ocular chitosan nanoparticle: formulation, optimization, characterization, ocular irritation, and antimicrobial activity

M Bin-Jumah, SJ Gilani, MA Jahangir… - International Journal …, 2020 - Taylor & Francis
Purpose The topically administered drugs through conventional delivery systems have low
bioavailability. Henceforth, the present study was designed to prepare and optimize …

[HTML][HTML] Design and development of novel bioadhesive niosomal formulation for the transcorneal delivery of anti-infective agent: In-vitro and ex-vivo investigations

Y Zubairu, LM Negi, Z Iqbal, S Talegaonkar - Asian journal of …, 2015 - Elsevier
Gatifloxacin eye drops are frequently used in eye infections. However such formulations
have a major drawback ie short duration of action and usually require 4–6 times installations …

[HTML][HTML] Investigation of moxifloxacin loaded chitosan–dextran nanoparticles for topical instillation into eye: In-vitro and ex-vivo evaluation

RA Kaskoos - International journal of pharmaceutical investigation, 2014 - ncbi.nlm.nih.gov
Methods: Formulation was optimized by 3-factors (CS, DS, and Mox concentration), 3-levels
(− 1, 0,+ 1) Box-Behnken design. Optimized formulation was characterized for various in …

Polymeric Inserts Containing Eudragit® L100 Nanoparticle for Improved Ocular Delivery of Azithromycin

S Taghe, S Mirzaeei, RG Alany, A Nokhodchi - Biomedicines, 2020 - mdpi.com
Polymeric inserts containing azithromycin-loaded Eudragit® L100 nanoparticles were
developed to sustain the drug release and enhance its ocular performance. The solvent …

Chitosan nanoparticles for meloxicam ocular delivery: development, in vitro characterization, and in vivo evaluation in a rabbit eye model

HB Mohamed, MA Attia Shafie, AI Mekkawy - Pharmaceutics, 2022 - mdpi.com
Eye inflammation is considered one of the most common co-morbidities associated with
ocular disorders and surgeries. Conventional management of this condition with non …

Preparation and evaluation of modified chitosan nanoparticles using anionic sodium alginate polymer for treatment of ocular disease

VA Bhosale, V Srivastava, B Valamla, R Yadav… - Pharmaceutics, 2022 - mdpi.com
Mucoadhesive nanoparticles offer prolonged drug residence time at the corneal epithelium
by adhering to the mucous layer of the eye. Here, in this research investigation, voriconazole …

Formulation and evaluation of nano lipid carrier-based ocular gel system: optimization to antibacterial activity

SJ Gilani, MN Jumah, A Zafar, SS Imam, M Yasir… - Gels, 2022 - mdpi.com
The present research work was designed to prepare Azithromycin (AM)-loaded nano lipid
carriers (NLs) for ocular delivery. NLs were prepared by the emulsification–homogenization …

Novel dexamethasone-loaded nanomicelles for the intermediate and posterior segment uveitis

RD Vaishya, M Gokulgandhi, S Patel, M Minocha… - Aaps Pharmscitech, 2014 - Springer
Abstract Development and characterization of dexamethasone (DEX)-encapsulated
polymeric nanomicelles have been reported. A low molecular weight di-block copolymer …