To identify genetic loci influencing central obesity and fat distribution, we performed a meta-
analysis of 16 genome-wide association studies (GWAS, N= 38,580) informative for adult …

Obesity is a major public health problem with strong genetic determination. Multiple genetic
variants have been implicated for obesity by conducting genome-wide association (GWA) …

Body fat distribution, particularly centralized obesity, is associated with metabolic risk above
and beyond total adiposity. We performed genome-wide association of abdominal adipose …

Genome-wide discovery efforts have identified more than 500 genetic loci associated with
adiposity traits. The vast majority of these loci were found through large-scale meta-analyses …

Background: To identify loci associated with abdominal fat and replicate prior findings, we
performed genome-wide association (GWA) studies of abdominal fat traits: subcutaneous …

Polymorphisms in adipokine genes, such as leptin (LEP), leptin receptor (LEPR), resistin
(RETN), adiponectin (ADIPOQ), interleukin‐1β (IL‐1β), IL‐6 (IL‐6), and tumor necrosis factor …

Waist-hip ratio (WHR) is a measure of body fat distribution and a predictor of metabolic
consequences independent of overall adiposity. WHR is heritable, but few genetic variants …

To date, genome-wide association studies (GWASs) have identified> 100 loci with single
variants associated with body mass index (BMI). This approach may miss loci with high …

To increase our understanding of the genetic basis of adiposity and its links to
cardiometabolic disease risk, we conducted a genome-wide association meta-analysis of …

Obesity is a major public health problem with a significant genetic component. Multiple DNA
polymorphisms/genes have been shown to be strongly associated with obesity, typically in …