Role of immunotherapy in breast cancer

SL Jacob, LA Huppert, HS Rugo - JCO Oncology Practice, 2023 - ascopubs.org
The advent of immunotherapy, particularly immune checkpoint inhibitors (ICIs), has
revolutionized the treatment of solid tumor malignancies. In breast cancer, the most robust …

[HTML][HTML] Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immunotherapy for the treatment of breast cancer

LA Emens, S Adams, A Cimino-Mathews… - … for immunotherapy of …, 2021 - ncbi.nlm.nih.gov
Breast cancer has historically been a disease for which immunotherapy was largely
unavailable. Recently, the use of immune checkpoint inhibitors (ICIs) in combination with …

Immune checkpoint inhibitors and novel immunotherapy approaches for breast cancer

M Cejuela, A Vethencourt, S Pernas - Current Oncology Reports, 2022 - Springer
Abstract Purpose of Review To critically review the existing evidence on immune checkpoint
inhibitors (ICIs) in early-stage and metastatic breast cancer and discuss emerging strategies …

Immunotherapy in breast cancer: current practice and clinical challenges

D de Melo Gagliato, AC Buzaid, J Perez-Garcia… - BioDrugs, 2020 - Springer
Immunotherapy is currently approved for a subset of patients diagnosed with advanced triple
negative breast cancer (TNBC), based on the phase III randomized controlled trial …

Clinical progress of PD-1/L1 inhibitors in breast cancer immunotherapy

F Chen, N Chen, Y Gao, L Jia, Z Lyu, J Cui - Frontiers in Oncology, 2022 - frontiersin.org
Breast cancer is a major killer of women's health worldwide. While breast cancer is thought
to have lower immunogenicity compared with other solid tumors, combination therapy is …

Role of immunotherapy in triple-negative breast cancer

TE Keenan, SM Tolaney - Journal of the National Comprehensive Cancer …, 2020 - jnccn.org
Immune checkpoint inhibitors (ICIs) have led to durable clinical remissions in many
metastatic cancers. However, the single-agent efficacy of ICIs in breast cancer is low …

Immunotherapy, an evolving approach for the management of triple negative breast cancer: Converting non-responders to responders

MF Tolba, HA Omar - Critical reviews in oncology/hematology, 2018 - Elsevier
Immunotherapy comprises a promising new era in cancer therapy. Immune checkpoint
inhibitors targeting either the programmed death (PD)-1 receptor or its ligand PD-L1 were …

Immunotherapy in breast cancer: an overview of current strategies and perspectives

V Debien, A De Caluwé, X Wang… - NPJ Breast …, 2023 - nature.com
Recent progress in immunobiology has led the way to successful host immunity
enhancement against breast cancer. In triple-negative breast cancer, the combination of …

Pembrolizumab in patients with advanced triple-negative breast cancer: phase Ib KEYNOTE-012 study

R Nanda, LQM Chow, EC Dees, R Berger… - Journal of Clinical …, 2016 - ascopubs.org
Purpose Immune checkpoint inhibition has been demonstrated to be an effective anticancer
strategy. Several lines of evidence support the study of immunotherapy in triple-negative …

Current status of PD-1/PD-L1 blockade immunotherapy in breast cancer

E Noguchi, T Shien, H Iwata - Japanese journal of clinical …, 2021 - academic.oup.com
Over the past 10 years, immunotherapy with immune checkpoint inhibitors has
revolutionized the management of various cancers. However, immunotherapy in breast …