Gut microbiota microbial metabolites in diabetic nephropathy patients: far to go

JX Yu, X Chen, SG Zang, X Chen, YY Wu… - Frontiers in Cellular …, 2024 - frontiersin.org
Diabetic nephropathy (DN) is one of the main complications of diabetes and a major cause
of end-stage renal disease, which has a severe impact on the quality of life of patients. Strict …

Impaired amino acid metabolism and its correlation with diabetic kidney disease progression in type 2 diabetes mellitus

H Zhu, M Bai, X Xie, J Wang, C Weng, H Dai, J Chen… - Nutrients, 2022 - mdpi.com
Background: Metabolomics is useful in elucidating the progression of diabetes; however, the
follow-up changes in metabolomics among health, diabetes mellitus, and diabetic kidney …

Optimization of kidney dysfunction prediction in diabetic kidney disease using targeted metabolomics

I Ibarra-González, I Cruz-Bautista, OY Bello-Chavolla… - Acta Diabetologica, 2018 - Springer
Aims Metabolomics have been used to evaluate the role of small molecules in human
disease. However, the cost and complexity of the methodology and interpretation of findings …

The pathogenic role of intestinal flora metabolites in diabetic nephropathy

E Tian, F Wang, L Zhao, Y Sun, J Yang - Frontiers in Physiology, 2023 - frontiersin.org
With the increasing incidence of diabetes, diabetic kidney disease has become a major
cause of chronic kidney disease. The role of the gut microbiota in diabetes and its related …

High-throughput metabolomics and diabetic kidney disease progression: evidence from the chronic renal insufficiency (CRIC) study

J Zhang, T Fuhrer, H Ye, B Kwan… - American journal of …, 2022 - karger.com
Introduction: Metabolomics could offer novel prognostic biomarkers and elucidate
mechanisms of diabetic kidney disease (DKD) progression. Via metabolomic analysis of …

Urine metabolomics reveals biomarkers and the underlying pathogenesis of diabetic kidney disease

M Luo, Z Zhang, Y Lu, W Feng, H Wu, L Fan… - … Urology and Nephrology, 2023 - Springer
Purpose Diabetic kidney disease (DKD) is the most common complication of type 2 diabetes
mellitus (T2DM), and its pathogenesis is not yet fully understood and lacks noninvasive and …

Role of gut microbiota, immune imbalance, and allostatic load in the occurrence and development of diabetic kidney disease

YZ Han, HJ Zheng, BX Du, Y Zhang… - Journal of Diabetes …, 2023 - Wiley Online Library
Diabetic kidney disease (DKD) is a prevailing complication arising from diabetes mellitus.
Unfortunately, there are no trustworthy and efficacious treatment modalities currently …

The human microbiome in chronic kidney disease: a double-edged sword

E Wehedy, IF Shatat, S Al Khodor - Frontiers in medicine, 2022 - frontiersin.org
Chronic kidney disease (CKD) is an increasing global health burden. Current treatments for
CKD include therapeutics to target factors that contribute to CKD progression, including …

[HTML][HTML] Intestinal microbiota and diabetic kidney diseases: the role of microbiota and derived metabolites inmodulation of renal inflammation and disease progression

CM Mosterd, M Kanbay, BJH Van Den Born… - Best Practice & …, 2021 - Elsevier
Diabetic kidney disease (DKD) represents a growing public health burden and is the leading
cause of end-stage kidney diseases. In recent years, host-gut microbiota interactions have …

Targeted metabolomics as a tool for the diagnosis of kidney disease in Type II diabetes mellitus

S Abdelsattar, ZA Kasemy, M Elsayed… - British Journal of …, 2021 - Taylor & Francis
Background: Diabetic kidney disease (DKD) is an increasing health problem and an extra
burden to health services. The study of characteristic metabolic alterations of DKD is crucial …