Intestinal microbiome diversity of diabetic and non-diabetic kidney disease: Current status and future perspective

S Das, R Gnanasambandan - Life Sciences, 2023 - Elsevier
A significant portion of the health burden of diabetic kidney disease (DKD) is caused by both
type 1 and type 2 diabetes which leads to morbidity and mortality globally. It is one of the …

Blood plasma metabolites in diabetes-associated chronic kidney disease: A focus on lipid profiles and cardiovascular risk

A Lecamwasam, T Mansell, EI Ekinci, R Saffery… - Frontiers in …, 2022 - frontiersin.org
Background We investigated a cross-sectional metabolomic analysis of plasma and urine of
patients with early and late stage diabetes associated chronic kidney disease (CKD) …

Metabolomics insights into pathophysiological mechanisms of nephrology

A Zhang, H Sun, S Qiu, X Wang - International urology and nephrology, 2014 - Springer
Kidney diseases (KD), a major public health problem that affects about 10% of the general
population, manifest in progressive loss of renal function, which ultimately leads to complete …

Chronic kidney disease: biomarker diagnosis to therapeutic targets

YN Wang, SX Ma, YY Chen, L Chen, BL Liu, QQ Liu… - Clinica Chimica …, 2019 - Elsevier
Chronic kidney disease (CKD), characterized as renal dysfunction, is recognized as a major
public health problem with high morbidity and mortality worldwide. Unfortunately, there are …

Genomics, proteomics and metabolomics approaches for predicting diabetic nephropathy in type 2 diabetes mellitus patients

S Darmayanti, R Lesmana, A Meiliana… - Current Diabetes …, 2021 - ingentaconnect.com
Background: There is a continuous rise in the prevalence of type 2 diabetes mellitus (T2DM)
worldwide and most patients are unaware of the presence of this chronic disease at the …

Metabolomics approaches for the diagnosis and understanding of kidney diseases

H Abbiss, GL Maker, RD Trengove - Metabolites, 2019 - mdpi.com
Diseases of the kidney are difficult to diagnose and treat. This review summarises the
definition, cause, epidemiology and treatment of some of these diseases including chronic …

Identification of biomarkers for development of end-stage kidney disease in chronic kidney disease by metabolomic profiling

T Kimura, K Yasuda, R Yamamoto, T Soga, H Rakugi… - Scientific reports, 2016 - nature.com
A critical issue in the management of chronic kidney disease (CKD) is to prevent patients
from the progression to end-stage kidney disease (ESKD), however, there is only limited …

[HTML][HTML] Early detection of diabetic kidney disease: Present limitations and future perspectives

CH Lin, YC Chang, LM Chuang - World journal of diabetes, 2016 - ncbi.nlm.nih.gov
Diabetic kidney disease (DKD) is one of the most common diabetic complications, as well as
the leading cause of chronic kidney disease and end-stage renal disease around the world …

Gut microbiota, key to unlocking the door of diabetic kidney disease

P Wang, T Wang, X Zheng, W Cui, J Shang… - Nephrology, 2021 - Wiley Online Library
This review discusses the influence of gut microbiota dysbiosis on diabetic kidney disease
through metabolite profile changes and immune and inflammatory mechanisms. We also …

Metabolomics in the study of kidney diseases

RH Weiss, K Kim - Nature Reviews Nephrology, 2012 - nature.com
Metabolomics—the nontargeted measurement of all metabolites produced by the body—is
beginning to show promise in both biomarker discovery and, in the form of …