Background Growing evidence suggests a complex bidirectional interaction between gut
microbes, gut-derived microbial metabolites, and diabetic kidney disease (DKD), known as …

Chronic kidney disease (CKD) is an increasingly prevalent medical condition associated
with high mortality and cardiovascular complications. The intricate interplay between kidney …

Introduction Metabolomics allows exploration of novel biomarkers and provides insights on
metabolic pathways associated with disease. To date, metabolomics studies on CKD have …

Kidney diseases still pose one of the biggest challenges for global health, and their
heterogeneity and often high comorbidity load seriously hinders the unraveling of their …

In this review of the application of proteomics and metabolomics to kidney disease research,
we review key concepts, highlight illustrative examples, and outline future directions. The …

The gut microbiota consists of trillions of microorganisms, fulfilling important roles in
metabolism, nutritional intake, physiology and maturation of the immune system, but also …

Globally, chronic kidney disease (CKD) contributes substantial morbidity and mortality.
Recently, various 'omics platforms have provided insight into the molecular basis of kidney …

Chronic kidney disease (CKD) is characterized by retention of uremic solutes. Compared to
patients with non-dialysis dependent CKD, those requiring haemodialysis (HD) have …

Diabetic kidney disease (DKD) is the leading cause of end-stage renal disease; however,
few biomarkers of its early identification are available. The aim of the study was to assess …

In chronic kidney disease (CKD), cardiovascular (CV) damage is present in parallel which
leads to an increased risk of CV disease. Both traditional and non-traditional risk factors …