RNA regulators are powerful components of the synthetic biology toolbox. Here, we expand
the repertoire of synthetic gene networks built from these regulators by constructing a …

Predictable and controllable tuning of genetic circuits to regulate gene expression, including
modulation of existing circuits or constructs without the need for redesign or rebuilding, is a …

RNA regulators are emerging as powerful tools to engineer synthetic genetic networks or
rewire existing ones. A potential strength of RNA networks is that they may be able to …

RNA transcriptional regulators are emerging as versatile components for genetic network
construction. However, these regulators suffer from incomplete repression in their OFF state …

RNA genetic circuitry is emerging as a powerful tool to control gene expression. However,
little work has been done to create a theoretical foundation for RNA circuit design. A …

The widespread natural ability of RNA to sense small molecules and regulate genes has
become an important tool for synthetic biology in applications as diverse as environmental …

The lack of signaling modularity of biomolecular systems poses major challenges toward
engineering complex networks. Directional signaling between an upstream and a …

One of the long-term goals of synthetic biology is to develop designable genetic parts with
predictable behaviors that can be utilized to implement diverse cellular functions. The …

Synthetic biology approaches life from the perspective of an engineer. Standardized and de
novo design of genetic parts to subsequently build reproducible and controllable modules …

Small regulatory RNAs (sRNAs) are short non-coding RNAs in bacteria capable of post-
transcriptional regulation. sRNAs have recently gained attention as tools in basic and …