Background Levels of sex hormone-binding globulin (SHBG) and the androgen testosterone
have been associated with risk of diseases throughout the lifecourse. Although both SHBG …

Background Testosterone is an essential sex hormone that plays a vital role in the overall
health and development of males. It is well known that obesity decreases testosterone …

Hypothyroidism and hyperthyroidism are observationally associated with sex hormone
concentrations and sexual dysfunction, but causality is unclear. We investigated whether …

Introduction This study aims to clarify the role (s) of endogenous sex hormones to influence
health outcomes in men, specifically to define the associations of plasma testosterone with …

Background: Testosterone levels are differentially linked with diabetes risk in men and
women: lower testosterone levels in men and higher testosterone levels in women are …

Low testosterone levels in men have been linked to decreased physical and mental function,
as well as a reduced quality of life. Previous prospective observational studies have …

TESTOSTERONE AND THE METABOLIC SYNDROME 207 of the syndrome conveys a
significantly increased risk of type 2 diabetes (T2DM) and cardiovascular disease, hence …

Life expectancy in the developed West is currently stagnated and remains shorter in men
than women. Well-established evolutionary biology theory suggests lifespan trades-off …

Objectives Testosterone concentrations in men decline with advancing age. However, the
cause of the decline is yet to be fully elucidated. Therefore, the aims of this study were to …

Objectives Observationally, testosterone is negatively associated with systemic
inflammation, but this association is open to both residual confounding and reverse …