Objective Serum testosterone concentrations are affected by factors unrelated to
hypothalamo‐pituitary‐testicular axis pathology. We evaluated the impact of …

As men age, testosterone levels decline, and decreased testosterone levels are associated
with increased risks of osteoporosis, metabolic syndrome, type 2 diabetes mellitus and …

Context: Low testosterone levels have been associated with outcomes that reduce survival
in men. Objective: Our objective was to perform a systematic review and meta-analysis of …

Objective Low total testosterone (TT) serum concentrations in men have been associated
with various cardiometabolic risk factors. But given error-prone immunoassays used for TT …

Context: Epidemiologic studies suggest that endogenous testosterone (T) levels in males
may be implicated in cardiovascular disease (CVD), however further clarification is needed …

Aims Observational evidence suggests associations between sex hormone levels and heart
failure (HF). We used sex‐specific genetic variants associated with androgenic sex hormone …

Context Observational studies show discordant links between endogenous testosterone
levels and cardiovascular diseases (CVD). Objective We assessed whether sex hormones …

Even though the levels of circulating sex steroid hormones are to a large extent heritable,
their genetic determinants are largely unknown. With the advent of genome-wide …

Background Type 2 diabetes is a risk factor for testosterone deficiency and impaired sex
steroid status. Some studies also investigated the association of testosterone level with …

Background. The strength of associations between total testosterone (TT) and metabolic
parameters may vary in different nature of population structure; however, no study has ever …