Testosterone acting via the androgen receptor, and via aromatisation to oestradiol, an
activator of the oestrogen receptor, plays key roles in adipose tissue, bone, and skeletal …

Many factors influence human facial morphology, including genetics, age, nutrition,
biomechanical forces, and endocrine factors. Moreover, facial features clearly differ between …

Context The literature provides no clear answer as to whether low endogenous testosterone
increases risk of cardiovascular disease (CVD) in healthy men. Objective Our purpose was …

Introduction The relationship between endogenous testosterone (T) levels and
cardiovascular (CV) risk in men is conflicting. Aim To verify whether endogenous T levels …

Objective. There is increasing evidence suggesting that low total testosterone concentration
is associated with incident type 2 diabetes mellitus (T2DM) in men. The aim of this study was …

Purpose The impact of endogenous androgen levels on the risk of type 2 diabetes in women
remains uncertain. The objective was to investigate associations between endogenous …

Sex hormones are hypothesized to drive sex-specific health disparities. Here, we study the
association between sex steroid hormones and DNA methylation-based (DNAm) biomarkers …

Context Evidence has shown maternal androgen levels in both the general population and
populations with hyperandrogenic disorders are inversely associated with offspring birth …

Objective In observational studies, testosterone has been reported to be associated with
some types of cancers. However, the direction and magnitude of the causal association …

Low testosterone is associated with mortality in multiple cohort studies; however, it is unclear
if this is a causal association or due to low testosterone being a biomarker of poor health …