The role of host genetics in susceptibility to severe viral infections in humans and insights into host genetics of severe COVID-19: A systematic review

A Elhabyan, S Elyaacoub, E Sanad, A Abukhadra… - Virus research, 2020 - Elsevier
Background Susceptibility to severe viral infections was reported to be associated with
genetic variants in immune response genes using case reports and GWAS studies. SARS …

Host genetic factors determining COVID-19 susceptibility and severity

TP Velavan, SR Pallerla, J Rüter, Y Augustin… - …, 2021 - thelancet.com
The COVID-19 pandemic caused by the Severe Acute Respiratory Syndrome Coronavirus-2
(SARS-CoV-2) poses an unprecedented challenge to humanity. SARS-CoV-2 infections …

Human genetic factors associated with susceptibility to SARS-CoV-2 infection and COVID-19 disease severity

C Anastassopoulou, Z Gkizarioti, GP Patrinos… - Human genomics, 2020 - Springer
Background The emergence of the novel coronavirus in Wuhan, Hubei Province, China, in
December 2019 marked the synchronization of the world to a peculiar clock that is counting …

Deciphering the role of host genetics in susceptibility to severe COVID-19

ME Carter-Timofte, SE Jørgensen, MR Freytag… - Frontiers in …, 2020 - frontiersin.org
Coronavirus disease-19 (COVID-19) describes a set of symptoms that develop following
infection by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Whilst …

[HTML][HTML] Genetic susceptibility to severe COVID-19

C Cappadona, V Rimoldi, EM Paraboschi… - Infection, Genetics and …, 2023 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the etiologic agent of the
coronavirus disease 2019 (COVID-19) pandemic. Clinical manifestations of the disease …

Clinical implications of host genetic variation and susceptibility to severe or critical COVID-19

CI van der Made, MG Netea, FL van der Veerdonk… - Genome medicine, 2022 - Springer
Since the start of the coronavirus disease 2019 (COVID-19) pandemic, important insights
have been gained into virus biology and the host factors that modulate the human immune …

Role of genetic variants and host polymorphisms on COVID‐19: From viral entrance mechanisms to immunological reactions

A Adli, M Rahimi, R Khodaie… - Journal of Medical …, 2022 - Wiley Online Library
Abstract Coronavirus disease 2019 (COVID‐19), caused by a highly pathogenic emerging
virus, is called severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). Knowledge …

Why do some people develop serious COVID-19 disease after infection, while others only exhibit mild symptoms?

M Ballow, CL Haga - The Journal of Allergy and Clinical Immunology: In …, 2021 - Elsevier
The year 2020 was a landmark year of a once-in-a-century pandemic of a novel coronavirus,
SARS-CoV-2 virus, that led to a rapidly spreading coronavirus disease (COVID-19). The …

Individual genetic variability mainly of Proinflammatory cytokines, cytokine receptors, and toll‐like receptors dictates pathophysiology of COVID‐19 disease

MK Vakil, Y Mansoori, GRL Al‐Awsi… - Journal of Medical …, 2022 - Wiley Online Library
Innate and acquired immunity responses are crucial for viral infection elimination. However,
genetic variations in coding genes may exacerbate the inflammation or initiate devastating …

Human gene polymorphisms and their possible impact on the clinical outcome of SARS-CoV-2 infection

SMA Hashemi, M Thijssen, SY Hosseini, A Tabarraei… - Archives of …, 2021 - Springer
The SARS-CoV-2 pandemic has become one of the most serious health concerns globally.
Although multiple vaccines have recently been approved for the prevention of coronavirus …