A thiol–thiosulfonate reaction providing a novel strategy for turn-on thiol sensing

C Ge, H Wang, B Zhang, J Yao, X Li, W Feng… - Chemical …, 2015 - pubs.rsc.org
The first thiol-specific turn-on probe, BODIPY-TS, utilizing a thiosulfonate scaffold as the thiol
recognition unit was reported. BODIPY-TS displays low toxicity, and features high sensitivity …

A highly selective and sensitive fluorescent thiol probe through dual-reactive and dual-quenching groups

H Zhang, C Zhang, R Liu, L Yi, H Sun - Chemical Communications, 2015 - pubs.rsc.org
A new fluorescent probe installed with dual-reactive and dual-quenching groups was
rationally designed for highly selective and sensitive sensing of biothiols. The sensitivity of …

A chemical covalent tactic for bio-thiol sensing and protein labeling agent design

L Zhang, J Kang, S Liu, X Zhang, J Sun, Y Hu… - Chemical …, 2020 - pubs.rsc.org
Discovering novel chemical reactions is important for bioanalysis. Herein, we report a tactic
for bio-thiol sensing and protein labeling agent design by the installation of a sulfoxide …

Naphthalimide scaffold provides versatile platform for selective thiol sensing and protein labeling

P Zhou, J Yao, G Hu, J Fang - ACS Chemical Biology, 2016 - ACS Publications
Reversible thiol modifications are fundamental of cellular redox regulation. Specific thiol
detection, including thiol sensing and protein thiols labeling, is critical to study such …

Recent progress in fluorescent probes for the detection of biothiols

S Wang, S Shen, Y Zhang, ZB Dai Xi - Chinese Journal of Organic …, 2014 - sioc-journal.cn
Intracellular thiols, such as cysteine (Cys), homocysteine (Hcy) and glutathione (GSH), play
crucial roles in maintaining biological systems. In last decade, developing small molecule …

Recent progress in luminescent and colorimetric chemosensors for detection of thiols

HS Jung, X Chen, JS Kim, J Yoon - Chemical Society Reviews, 2013 - pubs.rsc.org
In the past few decades, the development of optical probes for thiols has attracted great
attention because of the biological importance of the thiol-containing molecules such as …

A modular template for the design of thiol-triggered sensors and prodrugs

JR Knight, Y Wang, S Xu, W Chen, CE Berkman… - … Acta Part A: Molecular …, 2021 - Elsevier
A unique reaction between thiols (RSH) and alkyl sulfonylbenzothiazole was discovered.
This reaction was specific for thiols and produced a sulfinic acid (RSO 2 H) as the …

Thiol-addition reactions and their applications in thiol recognition

C Yin, F Huo, J Zhang, R Martinez-Manez… - Chemical Society …, 2013 - pubs.rsc.org
Because of the biological importance of thiols, the development of probes for thiols has been
an active research area in recent years. In this review, we summarize the results of recent …

A Deep Dive into Thiourea‐Based Sensors for Cation Sensing

A Khan, P Dawar, S De - ChemistrySelect, 2024 - Wiley Online Library
Thioureas are preferred structures in the disciplines of chemosensors, organic, and
pharmaceutical field. Thioureas, a class of tuneable organosulfur compounds, and their …

β-Cyclodextrin-promoted colorimetric and fluorescence turn-on probe for discriminating highly toxic thiophenol from biothiols

T Xu, S Zhao, X Wu, L Zeng, M Lan - ACS Sustainable Chemistry …, 2020 - ACS Publications
A complex that was composed of β-cyclodextrin (β-CD) and a flavone derivative (compound
5) was designed as a colorimetric and fluorescence turn-on probe to discriminate thiophenol …