Unraveling muscle impairment associated with COVID-19 and the role of 3D culture in its investigation

MLGA Seixas, LP Mitre, S Shams, GB Lanzuolo… - Frontiers in …, 2022 - frontiersin.org
COVID-19, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has
been considered a public health emergency, extensively investigated by researchers …

Post-COVID-19 acute sarcopenia: physiopathology and management

K Piotrowicz, J Gąsowski, JP Michel… - Aging clinical and …, 2021 - Springer
In this review, we discuss the pathophysiologic and management aspects of acute
sarcopenia in relation to SARS-CoV-2 infection. COVID-19 is as a multi-organ infectious …

Structural and functional impairments of skeletal muscle in patients with postacute sequelae of SARS-CoV-2 infection

M Colosio, L Brocca, MF Gatti, M Neri… - Journal of Applied …, 2023 - journals.physiology.org
Following acute coronavirus disease 2019 (COVID-19), a substantial proportion of patients
showed symptoms and sequelae for several months, namely the postacute sequelae of …

Myopathy as a cause of fatigue in long‐term post‐COVID‐19 symptoms: Evidence of skeletal muscle histopathology

EK Hejbøl, T Harbo, J Agergaard… - European Journal of …, 2022 - Wiley Online Library
Background and purpose Among post‐COVID‐19 symptoms, fatigue is reported as one of
the most common, even after mild acute infection, and as the cause of fatigue, myopathy …

Case report: myopathy in critically ill COVID-19 patients: a consequence of hyperinflammation?

V Versace, L Sebastianelli, D Ferrazzoli… - Frontiers in …, 2021 - frontiersin.org
Introduction: COVID-19-associated muscular complications may comprise myalgia,
weakness, wasting, and rhabdomyolysis. Skeletal muscle damage in COVID-19 may be due …

Skeletal muscle in hypoxia and inflammation: insights on the COVID-19 pandemic

FG Di Girolamo, N Fiotti, UG Sisto, A Nunnari… - Frontiers in …, 2022 - frontiersin.org
SARS-CoV-2 infection is often associated with severe inflammation, oxidative stress,
hypoxia and impaired physical activity. These factors all together contribute to muscle …

Acute skeletal muscle loss in SARS‐CoV‐2 infection contributes to poor clinical outcomes in COVID‐19 patients

A Attaway, N Welch, D Dasarathy… - Journal of cachexia …, 2022 - Wiley Online Library
Background Chronic disease causes skeletal muscle loss that contributes to morbidity and
mortality. There are limited data on the impact of dynamic muscle loss on clinical outcomes …

Neuromuscular complications of SARS-CoV-2 and other viral infections

S Jacob, R Kapadia, T Soule, H Luo… - Frontiers in …, 2022 - frontiersin.org
In this article we review complications to the peripheral nervous system that occur as a
consequence of viral infections, with a special focus on complications of severe acute …

[HTML][HTML] From heart to muscle: pathophysiological mechanisms underlying long-term physical sequelae from SARS-CoV-2 infection

C Serviente, ST Decker… - Journal of Applied …, 2022 - journals.physiology.org
The long-term sequelae of the coronavirus disease 2019 (COVID-19) are multifaceted and,
besides the lungs, impact other organs and tissues, even in cases of mild infection. Along …

Reduced muscle strength in patients with long-COVID-19 syndrome is mediated by limb muscle mass

R Ramírez-Vélez… - Journal of Applied …, 2023 - journals.physiology.org
Understanding the impact of COVID-19 on muscle strength may help to elucidate the organ
systems that contribute to acute and chronic COVID-19 sequelae. We questioned whether …