[HTML] nature.com

[HTML][HTML] Therapeutic potential of TRPM8 antagonists in prostate cancer

M Di Donato, C Ostacolo, P Giovannelli, V Di Sarno… - Scientific reports, 2021 - nature.com
Transient receptor potential melastatin-8 (TRPM8) represents an emerging target in prostate
cancer, although its mechanism of action remains unclear. Here, we have characterized and …
被引用次数：23 相关文章 所有 10 个版本
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[HTML][HTML] AMTB, a TRPM8 antagonist, suppresses growth and metastasis of osteosarcoma through repressing the TGFβ signaling pathway

Y Liu, A Leng, L Li, B Yang, S Shen, H Chen… - Cell death & …, 2022 - nature.com
Since its first identification in prostate cancers and prostate tissues, transient receptor
potential melastatin-subfamily member 8 (TRPM8) is subsequently found to be …
被引用次数：9 相关文章 所有 7 个版本
[HTML] spandidos-publications.com

[HTML][HTML] Overexpression of short TRPM8 variant α promotes cell migration and invasion, and decreases starvation-induced apoptosis in prostate cancer LNCaP cells

M Peng, Z Wang, Z Yang, L Tao, Q Liu… - Oncology …, 2015 - spandidos-publications.com
The aim of the present study was to investigate the function of a transient receptor potential
melastatin 8 (TRPM8) splice variant, short TRMP8α (sM8α), in the androgen‑dependent …
被引用次数：30 相关文章 所有 14 个版本
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[HTML][HTML] TRPM8-androgen receptor association within lipid rafts promotes prostate cancer cell migration

GP Grolez, DV Gordiendko, M Clarisse… - Cell death & …, 2019 - nature.com
In prostate carcinogenesis, androgens are known to control the expression of the transient
receptor potential melastatin 8 (TRPM8) protein via activation of androgen receptor (AR) …
被引用次数：41 相关文章 所有 13 个版本
[HTML] mdpi.com

[HTML][HTML] TRPM8 puts the chill on prostate cancer

GP Grolez, D Gkika - Pharmaceuticals, 2016 - mdpi.com
Prostate cancer (PCa) is one of the most frequently diagnosed cancers in developed
countries. Several studies suggest that variations in calcium homeostasis are involved in …
被引用次数：40 相关文章 所有 15 个版本

Identification of a natural compound, sesamin, as a novel TRPM8 antagonist with inhibitory effects on prostate adenocarcinoma

Y Sui, S Li, Y Zhao, Q Liu, Y Qiao, L Feng, S Li - Fitoterapia, 2020 - Elsevier
Transient receptor potential melastatin 8 (TRPM8) is a calcium ion-permeable cation
channel that is used as a prognostic marker and therapeutic target for different tumor types …
被引用次数：15 相关文章 所有 4 个版本
[HTML] nih.gov

[HTML][HTML] Knockdown of TRPM8 suppresses cancer malignancy and enhances epirubicin-induced apoptosis in human osteosarcoma cells

Y Wang, Z Yang, Z Meng, H Cao, G Zhu… - … Journal of Biological …, 2014 - ncbi.nlm.nih.gov
As the function of transient receptor potential melastatin member 8 (TRPM8) in
osteosarcoma is still unknown, we aim to investigate the possible effects and potential …
被引用次数：51 相关文章 所有 10 个版本
[HTML] mdpi.com

[HTML][HTML] Trpm4 in cancer—a new potential drug target

A Borgström, C Peinelt, P Stokłosa - Biomolecules, 2021 - mdpi.com
Transient receptor potential melastatin 4 (TRPM4) is widely expressed in various organs
and associated with cardiovascular and immune diseases. Lately, the interest in studies on …
被引用次数：33 相关文章 所有 9 个版本
[HTML] mdpi.com

[HTML][HTML] Trpm8 expression in human and mouse castration resistant prostate adenocarcinoma paves the way for the preclinical development of TRPM8-based …

S Genovesi, R Moro, B Vignoli, D De Felice… - Biomolecules, 2022 - mdpi.com
Metastatic prostate cancer (mPCa) is one of the leading causes of cancer-related mortality in
both the US and Europe. Androgen deprivation is the first-line therapy for mPCa; however …
被引用次数：14 相关文章 所有 13 个版本
[HTML] sciencedirect.com

[HTML][HTML] Small molecular inhibitors block TRPM4 currents in prostate cancer cells, with limited impact on cancer hallmark functions

A Borgstroem, B Hauert, S Kappel, E Zoni… - Journal of molecular …, 2021 - Elsevier
Transient receptor potential melastatin 4 (TRPM4) is a broadly expressed Ca 2+ activated
monovalent cation channel that contributes to the pathophysiology of several diseases. For …
被引用次数：20 相关文章 所有 9 个版本