Inherited platelet disorders may be the cause of bleeding symptoms of varying severity as
platelets fail to fulfil their haemostatic role after vessel injury. Platelet disorders may be …

Genetic defects of platelets give rise to bleeding syndromes of varying severity. Affected
areas of platelet function include the glycoprotein (GP) effectors of adhesion and …

Inherited platelet defects bleeding syndromes underlie of varying severity. The Bernard–
Soulier syndrome and Glanzmann thrombasthenia are disorders of membrane …

Genetic defects of the blood platelet membrane glycoproteins, GPIIb-IIIa (alpha IIb/beta 3;
CD41/CD61) and GPIb-V-IX (CD42) are the origin of several rare bleeding disorders, the …

The investigation of platelet defects causing bleeding disorders has been an important step
in determining the roles of the major glycoproteins in platelet function. In particular, Bernard …

Inherited platelet disorders (IPDs) are a heterogeneous group of diseases affecting platelet
production, morphology, and function. The degree of thrombocytopenia and functional …

Inherited disorders of platelets give rise to rare bleeding syndromes through defects of
platelet function and/or platelet production. Platelet function testing by biological and …

Inherited platelet disorders are rare bleeding syndromes due to either platelet function
abnormalities or thrombocytopenia which may be associated with functional defects. The …

The characterization of inherited diseases of platelets has provided valuable information
about platelet physiology and platelet protein function. Genetic studies on patients with …

Background and objectives: isolated platelet dense granule (PDG) deficiency is a
heterogeneous disorder frequently found among patients with mild to moderate bleeding …