The artificial sweetener acesulfame potassium affects the gut microbiome and body weight gain in CD-1 mice

X Bian, L Chi, B Gao, P Tu, H Ru, K Lu - PloS one, 2017 - journals.plos.org
Artificial sweeteners have been widely used in the modern diet, and their observed effects
on human health have been inconsistent, with both beneficial and adverse outcomes …

[HTML][HTML] Assessing the in vivo data on low/no-calorie sweeteners and the gut microbiota

AR Lobach, A Roberts, IR Rowland - Food and Chemical Toxicology, 2019 - Elsevier
Low/no-calorie sweeteners (LNCS) are continually under the spotlight in terms of their safety
and benefits; in 2014 a study was published linking LNCS to an enhanced risk of glucose …

Effects of the artificial sweetener neotame on the gut microbiome and fecal metabolites in mice

L Chi, X Bian, B Gao, P Tu, Y Lai, H Ru, K Lu - Molecules, 2018 - mdpi.com
Although artificial sweeteners are widely used in food industry, their effects on human health
remain a controversy. It is known that the gut microbiota plays a key role in human …

Non-caloric artificial sweeteners and the microbiome: findings and challenges

J Suez, T Korem, G Zilberman-Schapira, E Segal… - Gut …, 2015 - Taylor & Francis
Non-caloric artificial sweeteners (NAS) are common food supplements consumed by
millions worldwide as means of combating weight gain and diabetes, by retaining sweet …

Effects of low-dose non-caloric sweetener consumption on gut microbiota in mice

T Uebanso, A Ohnishi, R Kitayama, A Yoshimoto… - Nutrients, 2017 - mdpi.com
Non-caloric artificial sweeteners (NASs) provide sweet tastes to food without adding calories
or glucose. NASs can be used as alternative sweeteners for controlling blood glucose levels …

High-dose saccharin supplementation does not induce gut microbiota changes or glucose intolerance in healthy humans and mice

J Serrano, KR Smith, AL Crouch, V Sharma, F Yi… - Microbiome, 2021 - Springer
Background Non-caloric artificial sweeteners (NCAS) are widely used as a substitute for
dietary sugars to control body weight or glycemia. Paradoxically, some interventional studies …

Non-nutritive sweeteners possess a bacteriostatic effect and alter gut microbiota in mice

QP Wang, D Browman, H Herzog, GG Neely - PloS one, 2018 - journals.plos.org
Non-nutritive sweeteners (NNSs) are widely used in various food products and soft drinks.
There is growing evidence that NNSs contribute to metabolic dysfunction and can affect …

[HTML][HTML] Personalized microbiome-driven effects of non-nutritive sweeteners on human glucose tolerance

J Suez, Y Cohen, R Valdés-Mas, U Mor… - Cell, 2022 - cell.com
Non-nutritive sweeteners (NNS) are commonly integrated into human diet and presumed to
be inert; however, animal studies suggest that they may impact the microbiome and …

Reshaping the gut microbiota: Impact of low calorie sweeteners and the link to insulin resistance?

JE Nettleton, RA Reimer, J Shearer - Physiology & behavior, 2016 - Elsevier
Disruption in the gut microbiota is now recognized as an active contributor towards the
development of obesity and insulin resistance. This review considers one class of dietary …

Long-term consumption of the sugar substitute sorbitol alters gut microbiome and induces glucose intolerance in mice

CH Li, CT Wang, YJ Lin, HY Kuo, JS Wu, TC Hong… - Life Sciences, 2022 - Elsevier
Aims Epidemic obesity and diabetes have led to increased use of low-calorie sweeteners.
Although several studies have suggested that consumption of artificial sweeteners, such as …