[HTML][HTML] Cytokine elevation in severe and critical COVID-19: a rapid systematic review, meta-analysis, and comparison with other inflammatory syndromes
The description of a so-called cytokine storm in patients with COVID-19 has prompted
consideration of anti-cytokine therapies, particularly interleukin-6 antagonists. However …
consideration of anti-cytokine therapies, particularly interleukin-6 antagonists. However …
[HTML][HTML] Characterization of the cytokine storm reflects hyperinflammatory endothelial dysfunction in COVID-19
JT Sims, V Krishnan, CY Chang, SM Engle… - Journal of Allergy and …, 2021 - Elsevier
Background Physicians treating patients with coronavirus disease 2019 (COVID-19)
increasingly believe that the hyperinflammatory acute stage of COVID-19 results in a …
increasingly believe that the hyperinflammatory acute stage of COVID-19 results in a …
[HTML][HTML] COVID-19: Unanswered questions on immune response and pathogenesis
The novel coronavirus disease 2019 has rapidly increased in pandemic scale since it first
appeared in Wuhan, China, in December 2019. In these troubled days the scientific …
appeared in Wuhan, China, in December 2019. In these troubled days the scientific …
Is severe COVID-19 a cytokine storm syndrome: a hyperinflammatory debate
P Mehta, DC Fajgenbaum - Current opinion in Rheumatology, 2021 - journals.lww.com
Hyperinflammation is a key component of severe COVID-19, residing underneath the
cytokine storm umbrella term, associated with poor outcomes. Better understanding of the …
cytokine storm umbrella term, associated with poor outcomes. Better understanding of the …
[HTML][HTML] COVID-19: immunopathogenesis and Immunotherapeutics
L Yang, S Liu, J Liu, Z Zhang, X Wan… - Signal transduction and …, 2020 - nature.com
The recent novel coronavirus disease (COVID-19) outbreak, caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), is seeing a rapid increase in infected …
respiratory syndrome coronavirus 2 (SARS-CoV-2), is seeing a rapid increase in infected …
[HTML][HTML] Cytokine storm in COVID-19: immunopathogenesis and therapy
C Zanza, T Romenskaya, AC Manetti, F Franceschi… - Medicina, 2022 - mdpi.com
A cytokine storm is a hyperinflammatory state secondary to the excessive production of
cytokines by a deregulated immune system. It manifests clinically as an influenza-like …
cytokines by a deregulated immune system. It manifests clinically as an influenza-like …
[HTML][HTML] Coronavirus disease 2019 (COVID-19): cytokine storms, hyper-inflammatory phenotypes, and acute respiratory distress syndrome
S Lin, Y Zhao, D Zhou, F Zhou, F Xu - Genes & Diseases, 2020 - Elsevier
Abstract Coronavirus Disease 2019 (COVID-19) was first identified in China at the end of
2019. Acute respiratory distress syndrome (ARDS) represents the most common and serious …
2019. Acute respiratory distress syndrome (ARDS) represents the most common and serious …
[HTML][HTML] Immunopathology of Hyperinflammation in COVID-19
JN Gustine, D Jones - The American journal of pathology, 2021 - Elsevier
The rapid spread of coronavirus disease 2019 (COVID-19), caused by severe acute
respiratory syndrome–coronavirus 2 (SARS-CoV-2), has resulted in an unprecedented …
respiratory syndrome–coronavirus 2 (SARS-CoV-2), has resulted in an unprecedented …
[HTML][HTML] The dynamic changes in cytokine responses in COVID-19: a snapshot of the current state of knowledge
M Buszko, JH Park, D Verthelyi, R Sen, HA Young… - Nature …, 2020 - nature.com
“The role of cytokines in COVID-19” online symposium was presented on 18 June 2020 by
the NIH/FDA Immunology and Cytokine Interest Groups and was purposed to discuss our …
the NIH/FDA Immunology and Cytokine Interest Groups and was purposed to discuss our …
Immunopathology and immunotherapeutic strategies in severe acute respiratory syndrome coronavirus 2 infection
S Keam, D Megawati, SK Patel, R Tiwari… - Reviews in Medical …, 2020 - Wiley Online Library
The outbreak of coronavirus disease 2019 (COVID‐19) and pandemic, caused by severe
acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), has become a major concern …
acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), has become a major concern …