Background To understand the dynamics of infectious diseases, genomic epidemiology is
increasingly advocated, with a need for rapid generation of genetic sequences during …

Recently, protocols for amplicon based whole genome sequencing using Nanopore
technology have been described for Ebola virus, Zika virus, yellow fever virus and West Nile …

Whole genome sequencing can be used to characterize and to trace viral outbreaks.
Nanopore-based whole genome sequencing protocols have been described for several …

Background The recent global emergence and re-emergence of arboviruses has caused
significant human disease. Common vectors, symptoms and geographical distribution make …

Genome sequencing has become a powerful tool for studying emerging infectious diseases;
however, genome sequencing directly from clinical samples (ie, without isolation and …

Background Fast, specific identification and surveillance of pathogens is the cornerstone of
any outbreak response system, especially in the case of emerging infectious diseases and …

The capability of high-throughput sequencing (HTS) for detection of known and unknown
viruses timely makes it a powerful tool for public health emergency response. Third …

Metagenomic next-generation sequencing (mNGS), the shotgun sequencing of RNA and
DNA from clinical samples, has proved useful for broad-spectrum pathogen detection and …

Background Outbreaks of fever of unknown origin start with nonspecific symptoms and case
definition is only slowly developed and adapted, therefore, identifying the causative agent is …

The 2022 multi-country monkeypox (mpox) outbreak concurrent with the ongoing COVID-19
pandemic has further highlighted the need for genomic surveillance and rapid pathogen …